| Literature DB >> 20352528 |
Liang Xu1, Yu-Yan Tan, Jian-Qing Ding, Sheng-Di Chen.
Abstract
More recently, reprogramming of somatic cells to an embryonic stem cell-like state presents a milestone in the realm of stem cells, making it possible to derive all cell types from any patients bearing specific genetic mutations. With the development of induced pluripotent stem (iPS) cells, we are now able to use the derivatives of iPS cells to study the mechanisms of disease and to perform drug screening and toxicology testing. In addition, differentiated iPS cells are now close to be used in clinical practice. Here we review the progress of iPS technique and the possible application in the area of Parkinson's disease treatment.Entities:
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Year: 2010 PMID: 20352528 DOI: 10.1007/s12015-010-9145-2
Source DB: PubMed Journal: Stem Cell Rev Rep ISSN: 2629-3277 Impact factor: 5.739