Literature DB >> 20352063

EXPLORATION OF BRAVERMAN REACTION CHEMISTRY. SYNTHESIS OF TRICYCLIC DIHYDROTHIOPHENE DIOXIDE DERIVATIVES FROM BISPROPARGYL SULFONES.

Ken S Feldman1, Brandon R Selfridge.   

Abstract

The base-mediated bicyclization of unsymmetrical bispropargyl sulfones furnishes varying yields of dihydroisobenzothiophene dioxides through a presumed diradical intermediate. Attempts to trap a putative thiophene dioxide intermediate via Diels-Alder reaction with a pendant alkyne were not successful.

Entities:  

Year:  2010        PMID： 20352063      PMCID： PMC2844783          DOI： 10.3987/COM-09-11840

Source DB:  PubMed          Journal:  Heterocycles        ISSN： 0385-5414            Impact factor:   0.831


  4 in total

1.  Sequential intermediates in the base-catalyzed conversion of bis(pi-conjugated propargyl) sulfones to 1,3-dihydrobenzo- and naphtho[c]thiophene-2,2-dioxides.

Authors:  Yossi Zafrani; Hugo E Gottlieb; Milon Sprecher; Samuel Braverman
Journal:  J Org Chem       Date:  2005-11-25       Impact factor: 4.354

2.  Oxathiolene oxide synthesis via chelation-controlled addition of organometallic reagents to alkynols followed by addition of sulfur electrophiles and evaluation of oxathiolene oxides as anticarcinogenic enzyme inducers.

Authors:  Marion A Franks; Edward A Schrader; E Christine Pietsch; Daniel R Pennella; Suzy V Torti; Mark E Welker
Journal:  Bioorg Med Chem       Date:  2005-03-15       Impact factor: 3.641

3.  Synthesis of cyclo-1,3-dien-5-ynes.

Authors:  H Hopf; A Krüger
Journal:  Chemistry       Date:  2001-10-15       Impact factor: 5.236

4.  Synthesis of the parent and substituted tetracyclic ABCD ring cores of camptothecins via 1-(3-aryl-2-propynyl)- 1,6-dihydro-6-oxo-2-pyridinecarbonitriles.

Authors:  Weixiang Dai; Jeffrey L Petersen; Kung K Wang
Journal:  Org Lett       Date:  2006-09-28       Impact factor: 6.005
  4 in total
  2 in total

1.  Total Synthesis of (±)-Dragmacidin E: Problems Solved and Lessons Learned.

Authors:  Ken S Feldman; Paiboon Ngernmeesri
Journal:  Synlett       Date:  2012-08       Impact factor: 2.454

2.  Cytotoxic Alkylynols of the Sponge Cribrochalina vasculum: Structure, Synthetic Analogs and SAR Studies.

Authors:  Dimitry Kovalerchik; Ana Zovko; Petra Hååg; Adam Sierakowiak; Kristina Viktorsson; Rolf Lewensohn; Micha Ilan; Shmuel Carmeli
Journal:  Mar Drugs       Date:  2022-04-13       Impact factor: 6.085
  2 in total

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