| Literature DB >> 2035025 |
Abstract
The ability to mark a cell and its descendants genetically so that the resulting cell clone can be distinguished from neighboring cells facilitates studies in animal biology and development. A method of generating clones by inducing homologous mitotic recombination in Drosophila with a site-specific yeast recombinase is described. This method allows for frequent mosaicism after mitotic exchange is induced at predefined sites in the genome.Entities:
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Year: 1991 PMID: 2035025 DOI: 10.1126/science.2035025
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728