Literature DB >> 20348978

Multicentre study of bone tumours.

D C Obalum1, S U Eyesan, C N Ogo, G O Enweluzo.   

Abstract

BACKGROUND: Bone tumours are associated with high morbidity and mortality, especially in Lagos where late presentation, lack of diagnostic and therapeutic facilities as well as cultural and religious beliefs/practices constitute a formidable challenge to appropriate management.
OBJECTIVE: To study the clinico-pathologic pattern of primary bone tumours in Lagos.
METHODS: A 2.5 decade retrospective review of cases of primary bone tumours at National Orthopaedic Hospital, Lagos (NOH), Lagos University Teaching Hospital (LUTH), and Havana Specialist Hospital (HSH) was done. Data such as age, gender, tumour type were extracted from the medical records and analysed.
RESULTS: Six hundred and ninety-eight (698) cases were reviewed. 364 cases were from NOH, 242 from LUTH and 92 from HSH. There were 10 cases in 1981, 13 in 1985, 19 in 1990, 30 in 1995, 38 in 2000 and 46 in 2005. The age range of cases was 6 to 85 years with a mean of 25.8 years and peak frequency in the 11-20 year age group. 423 patients (60.6%) were males and 275(39.4%) were females giving a male to female ratio of 1.5: 1. Three hundred and fifty-six (51.0%) were of benign while 342 (49.0%) were malignant. The commonest types were osteosarcoma 197 cases (28.2%), osteochondroma 106 cases (15.2%) and osteoclastoma 78 cases (11.2%)
CONCLUSION: Primary bone tumours presenting to hospitals in Lagos are on the rise. They are common amongst males and teenagers. Majority are benign and comprise osteochondroma, osteosarcoma, osteoclastoma, aneurysmal bone cysts and chondrosarcoma.

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Mesh:

Year:  2010        PMID: 20348978

Source DB:  PubMed          Journal:  Niger Postgrad Med J


  3 in total

1.  Pattern of primary tumors and tumor-like lesions of bone in children: retrospective survey of biopsy results.

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Journal:  Int J Clin Exp Pathol       Date:  2015-09-01

2.  Osteochondroma: Review of 431 patients from one medical institution in South China.

Authors:  Kai Tong; Hongzhe Liu; Xiang Wang; Ziyi Zhong; Shenglu Cao; Chengjie Zhong; YunPing Yang; Gang Wang
Journal:  J Bone Oncol       Date:  2017-08-30       Impact factor: 4.072

3.  Overview of extremity musculoskeletal neoplasms at the Ahmadu Bello University Teaching Hospital Zaria, Nigeria.

Authors:  Maitama Mohammed Inuwa; Lawal Yau Zakariyau; Dahiru I Ismail; Ejagwulu S Friday; Aniko A Ibrahim; Abdulmalik A Mohammed
Journal:  Ann Afr Med       Date:  2017 Jul-Sep
  3 in total

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