Literature DB >> 20347792

Genetics of atrial fibrillation.

Steven A Lubitz1, B Alexander Yi, Patrick T Ellinor.   

Abstract

Recent studies of atrial fibrillation (AF) have identified mutations in a series of ion channels; however, these mutations appear to be relatively rare causes of AF. A genome-wide association study has identified novel variants on chromosome 4 associated with AF, although the mechanism of action for these variants remains unknown. Ultimately, a greater understanding of the genetics of AF should yield insights into novel pathways, therapeutic targets, and diagnostic testing for this common arrhythmia. Copyright (c) 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 20347792      PMCID： PMC3073057          DOI： 10.1016/j.hfc.2009.12.004

Source DB:  PubMed          Journal:  Heart Fail Clin        ISSN： 1551-7136            Impact factor:   3.179


  67 in total

1.  Mutations in the long QT gene, KCNQ1, are an uncommon cause of atrial fibrillation.

Authors:  P T Ellinor; R K Moore; K K Patton; J N Ruskin; M R Pollak; C A Macrae
Journal:  Heart       Date:  2004-12       Impact factor: 5.994

2.  A haplotype map of the human genome.

Authors: 
Journal:  Nature       Date:  2005-10-27       Impact factor: 49.962

3.  Genome-wide linkage scan identifies a novel genetic locus on chromosome 5p13 for neonatal atrial fibrillation associated with sudden death and variable cardiomyopathy.

Authors:  Carlos Oberti; Lejin Wang; Lin Li; Jiamei Dong; Shaoqi Rao; Wei Du; Qing Wang
Journal:  Circulation       Date:  2004-12-13       Impact factor: 29.690

4.  Familial aggregation in lone atrial fibrillation.

Authors:  Patrick T Ellinor; Danita M Yoerger; Jeremy N Ruskin; Calum A MacRae
Journal:  Hum Genet       Date:  2005-11-15       Impact factor: 4.132

5.  A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation.

Authors:  Min Xia; Qingfeng Jin; Saïd Bendahhou; Yusong He; Marie-Madeleine Larroque; Yiping Chen; Qinshu Zhou; Yiqing Yang; Yi Liu; Ban Liu; Qian Zhu; Yanting Zhou; Jie Lin; Bo Liang; Li Li; Xiongjian Dong; Zhiwen Pan; Rongrong Wang; Haiying Wan; Weiqin Qiu; Wenyuan Xu; Petra Eurlings; Jacques Barhanin; Yihan Chen
Journal:  Biochem Biophys Res Commun       Date:  2005-07-15       Impact factor: 3.575

6.  Relation of 97T polymorphism in KCNE5 to risk of atrial fibrillation.

Authors:  Lasse S Ravn; Jacob Hofman-Bang; Ulrik Dixen; Severin Olesen Larsen; Gorm Jensen; Stig Haunsø; Jesper Hastrup Svendsen; Michael Christiansen
Journal:  Am J Cardiol       Date:  2005-08-01       Impact factor: 2.778

7.  Familial aggregation of atrial fibrillation in Iceland.

Authors:  David O Arnar; Sverrir Thorvaldsson; Teri A Manolio; Gudmundur Thorgeirsson; Kristleifur Kristjansson; Hakon Hakonarson; Kari Stefansson
Journal:  Eur Heart J       Date:  2006-01-20       Impact factor: 29.983

8.  De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero.

Authors:  Kui Hong; David R Piper; Aurora Diaz-Valdecantos; Josep Brugada; Antonio Oliva; Elena Burashnikov; José Santos-de-Soto; Josefina Grueso-Montero; Ernesto Diaz-Enfante; Pedro Brugada; Frank Sachse; Michael C Sanguinetti; Ramon Brugada
Journal:  Cardiovasc Res       Date:  2005-08-18       Impact factor: 10.787

9.  Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine.

Authors:  Anne Schenzer; Thomas Friedrich; Michael Pusch; Paul Saftig; Thomas J Jentsch; Joachim Grötzinger; Michael Schwake
Journal:  J Neurosci       Date:  2005-05-18       Impact factor: 6.167

10.  Dosage requirement of Pitx2 for development of multiple organs.

Authors:  P J Gage; H Suh; S A Camper
Journal:  Development       Date:  1999-10       Impact factor: 6.868
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  18 in total

1.  Repolarization recipes for atrial fibrillation: beyond single channel variants.

Authors:  Dawood Darbar; Babar Parvez; Robert Abraham
Journal:  J Am Coll Cardiol       Date:  2012-03-13       Impact factor: 24.094

2.  Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes.

Authors:  James F Meschia; Donna K Arnett; Hakan Ay; Robert D Brown; Oscar R Benavente; John W Cole; Paul I W de Bakker; Martin Dichgans; Kimberly F Doheny; Myriam Fornage; Raji P Grewal; Katrina Gwinn; Christina Jern; Jordi Jimenez Conde; Julie A Johnson; Katarina Jood; Cathy C Laurie; Jin-Moo Lee; Arne Lindgren; Hugh S Markus; Patrick F McArdle; Leslie A McClure; Braxton D Mitchell; Reinhold Schmidt; Kathryn M Rexrode; Stephen S Rich; Jonathan Rosand; Peter M Rothwell; Tatjana Rundek; Ralph L Sacco; Pankaj Sharma; Alan R Shuldiner; Agnieszka Slowik; Sylvia Wassertheil-Smoller; Cathie Sudlow; Vincent N S Thijs; Daniel Woo; Bradford B Worrall; Ona Wu; Steven J Kittner
Journal:  Stroke       Date:  2013-09-10       Impact factor: 7.914

Review 3.  Addressing Multimorbidity and Polypharmacy in Individuals With Atrial Fibrillation.

Authors:  Fahad Shaikh; Lachlan B Pasch; Phillip J Newton; Beata V Bajorek; Caleb Ferguson
Journal:  Curr Cardiol Rep       Date:  2018-03-24       Impact factor: 2.931

Review 4.  Mechanisms and Drug Development in Atrial Fibrillation.

Authors:  David Calvo; David Filgueiras-Rama; José Jalife
Journal:  Pharmacol Rev       Date:  2018-07       Impact factor: 25.468

Review 5.  Atrial Fibrillation - A Common Ground for Neurology and Cardiology.

Authors:  Fawzi Abukhalil; Aakash Bodhit; Peter Y Cai; Saeed Ansari; Spandana Thenkabail; Sarah Ganji; Pradeepan Saravanapavan; Chandana Chandra Shekhar; Michael F Waters; Thomas M Beaver; Vishnumurthy Shushrutha Hedna
Journal:  J Atr Fibrillation       Date:  2013-08-31

6.  Augmented rififylin is a risk factor linked to aberrant cardiomyocyte function, short-QT interval and hypertension.

Authors:  Kathirvel Gopalakrishnan; Eric E Morgan; Shane Yerga-Woolwine; Phyllis Farms; Sivarajan Kumarasamy; Andrea Kalinoski; Xiaochen Liu; Jian Wu; Lijun Liu; Bina Joe
Journal:  Hypertension       Date:  2011-02-28       Impact factor: 10.190

7.  Mutation spectrum of the GATA4 gene in patients with idiopathic atrial fibrillation.

Authors:  Jun Wang; Yu-Min Sun; Yi-Qing Yang
Journal:  Mol Biol Rep       Date:  2012-05-03       Impact factor: 2.316

Review 8.  Cardiovascular risk factors for acute stroke: Risk profiles in the different subtypes of ischemic stroke.

Authors:  Adrià Arboix
Journal:  World J Clin Cases       Date:  2015-05-16       Impact factor: 1.337

9.  Pathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network.

Authors:  Hakan Ay; Ethem Murat Arsava; Gunnar Andsberg; Thomas Benner; Robert D Brown; Sherita N Chapman; John W Cole; Hossein Delavaran; Martin Dichgans; Gunnar Engström; Eva Giralt-Steinhauer; Raji P Grewal; Katrina Gwinn; Christina Jern; Jordi Jimenez-Conde; Katarina Jood; Michael Katsnelson; Brett Kissela; Steven J Kittner; Dawn O Kleindorfer; Daniel L Labovitz; Silvia Lanfranconi; Jin-Moo Lee; Manuel Lehm; Robin Lemmens; Chris Levi; Linxin Li; Arne Lindgren; Hugh S Markus; Patrick F McArdle; Olle Melander; Bo Norrving; Leema Reddy Peddareddygari; Annie Pedersén; Joanna Pera; Kristiina Rannikmäe; Kathryn M Rexrode; David Rhodes; Stephen S Rich; Jaume Roquer; Jonathan Rosand; Peter M Rothwell; Tatjana Rundek; Ralph L Sacco; Reinhold Schmidt; Markus Schürks; Stephan Seiler; Pankaj Sharma; Agnieszka Slowik; Cathie Sudlow; Vincent Thijs; Rebecca Woodfield; Bradford B Worrall; James F Meschia
Journal:  Stroke       Date:  2014-11-06       Impact factor: 7.914

10.  Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm.

Authors:  Iris I Müller; David B Melville; Vineeta Tanwar; Witold M Rybski; Amrita Mukherjee; M Benjamin Shoemaker; Wan-Der Wang; John A Schoenhard; Dan M Roden; Dawood Darbar; Ela W Knapik; Antonis K Hatzopoulos
Journal:  Dis Model Mech       Date:  2012-12-07       Impact factor: 5.758
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