Literature DB >> 203474

Effect of low density lipoprotein on proteoglycan synthesis by aorta cells in culture.

K Ehrlich, M Murray.   

Abstract

Increasing the content of human serum low density lipoprotein in the growth medium led to greater incorporation of 35S-sulfate into proteoglycan (mostly into dermatan sulfate) by primary aorta cells but did not affect similar incorporation by fibroblast cells. These results suggest a mechanism which can explain the increased deposition of lipid in aorta due to hyperlipidemia.

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Year:  1978        PMID： 203474     DOI： 10.1007/bf01944662

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  16 in total

1.  Uptake of radiosulphate by mucopolysaccharides of aorta in cholesterol-fed cockerels.

Authors:  K KOWALEWSKI
Journal:  Proc Soc Exp Biol Med       Date:  1959-07

2.  The influence of experimentally induced atherosclerosis on the sulfate content of the aortic wall.

Authors:  D T FORMAN; D S McCANN; R E MOSHER; A J BOYLE
Journal:  Circ Res       Date:  1960-01       Impact factor: 17.367

3.  Unified concept on the role of acid mucopolysaccharides and connective tissue proteins in the accumulation of lipids, lipoproteins, and calcium in the atherosclerotic plaque.

Authors:  W Hollander
Journal:  Exp Mol Pathol       Date:  1976-08       Impact factor: 3.362

4.  The interaction between human plasma lipoproteins and connective tissue glycosaminoglycans.

Authors:  P H Iverius
Journal:  J Biol Chem       Date:  1972-04-25       Impact factor: 5.157

5.  Acid mucopolysaccharides of human aorta. 2. Variations with atherosclerotic involvement.

Authors:  V Kumar; G S Berenson; H Ruiz; E R Dalferes; J P Strong
Journal:  J Atheroscler Res       Date:  1967 Sep-Oct

6.  Chemical and metabolic heterogeneity of a bovine aorta chondroitin sulfate-dermatan sulfate proteoglycan.

Authors:  H Kresse; H Heidel; E Buddecke
Journal:  Eur J Biochem       Date:  1971-10-26

7.  Electrophoretic separation of plasma lipoproteins in agarose gel.

Authors:  R P Noble
Journal:  J Lipid Res       Date:  1968-11       Impact factor: 5.922

8.  Composition of connective tissue in aortas from rhesus monkeys during regression of diet-induced fatty streaks.

Authors:  B Radhakrishnamurthy; D A Eggen; M Kokatnur; S Jirge; J P Strong; G S Berenson
Journal:  Lab Invest       Date:  1975-08       Impact factor: 5.662

9.  Proteoglycans in primate arteries. II. Synthesis and secretion of glycosaminoglycans by arterial smooth muscle cells in culture.

Authors:  T N Wight; R Ross
Journal:  J Cell Biol       Date:  1975-12       Impact factor: 10.539

10.  Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis.

Authors:  R Ross; J A Glomset
Journal:  Science       Date:  1973-06-29       Impact factor: 47.728
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  3 in total

1.  Effect of low-density lipoproteins on the synthesis and secretion of proteoglycans by human endothelial cells in culture.

Authors:  P Vijayagopal; S R Srinivasan; E R Dalferes; B Radhakrishnamurthy; G S Berenson
Journal:  Biochem J       Date:  1988-10-15       Impact factor: 3.857

2.  Proteoglycans in the microvasculature. I. Histochemical localization in microvessels of the rabbit eye.

Authors:  D H Ausprunk; C L Boudreau; D A Nelson
Journal:  Am J Pathol       Date:  1981-06       Impact factor: 4.307

3.  Effect of endothelium on glycosaminoglycan accumulation in injured rabbit aorta.

Authors:  T N Wight; K D Curwen; M M Litrenta; D R Alonso; C R Minick
Journal:  Am J Pathol       Date:  1983-11       Impact factor: 4.307
  3 in total

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