Literature DB >> 203472

Modification of theophylline-induced lipolysis in human fat cells after trypsination.

Y Giudicelli, D Brullé, R Nordmann.   

Abstract

Trypsin-treatment of human fat cells results in the potentiation of the lipolytic response and the cAMP accumulation induced by theophylline (5 . 10(-4) M) but not of those induced by theophylline (5 . 10(-3) M). The amount of cAMP formed after exposure to theophylline (5 . 10(-3) M) plus norepinephrine (5 . 10(-6) M) remains, however, 2.6 fold higher in trypsin-treated human fat cells than in the control ones.

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Year:  1978        PMID： 203472     DOI： 10.1007/bf01944651

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  Effects of sulfhydryl inhibition on the regulation of basal lipolysis and glucose uptake in human adipose tissue.

Authors:  Y Giudicelli; D Provins; R Nordmann
Journal:  Biochem Pharmacol       Date:  1975-05-01       Impact factor: 5.858

2.  METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS.

Authors:  M RODBELL
Journal:  J Biol Chem       Date:  1964-02       Impact factor: 5.157

3.  Phosphodiesterase activity of rat and human adipose tissue.

Authors:  S S Solomon
Journal:  J Lab Clin Med       Date:  1972-04

4.  The in vitro 14 C-cyclic AMP production by normal human adipose tissue in response to some hormones and in uncontrolled and controlled diabetic adipose tissue.

Authors:  A H Kissebah; T R Fraser
Journal:  Horm Metab Res       Date:  1972-03       Impact factor: 2.936

5.  Effect of dibutyryl-3',5'-AMP, theophylline and norepinephrine on lipolytic action of growth hormone and glucocorticoid in white fat cells.

Authors:  J N Fain
Journal:  Endocrinology       Date:  1968-04       Impact factor: 4.736

Review 6.  Biochemical aspects of drug and hormone action on adipose tissue.

Authors:  J N Fain
Journal:  Pharmacol Rev       Date:  1973-03       Impact factor: 25.468

7.  Influence of trypsin on lipolysis in human fat cells. Comparison with rat adipocytes.

Authors:  Y Giudicelli; D Provin; R Pecquery; R Nordmann
Journal:  Biochim Biophys Acta       Date:  1976-12-20

8.  Adenosine 3',5'-phosphate in biological materials. I. Purification and properties of cyclic 3',5'-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3',5'-phosphate in human urine.

Authors:  R W BUTCHER; E W SUTHERLAND
Journal:  J Biol Chem       Date:  1962-04       Impact factor: 5.157
  8 in total

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