| Literature DB >> 20345132 |
Kristofer J Thurecht1, Idriss Blakey, Hui Peng, Oliver Squires, Steven Hsu, Cameron Alexander, Andrew K Whittaker.
Abstract
We have demonstrated the design and synthesis of hyperbranched molecules that can be successfully imaged in vivo using (19)F MRI in under 10 min. These polymers are cytocompatible following chain extension with PEGMA. In addition, functionalization of these macromolecules can be achieved in a facile manner and with accessible and correct ligand presentation. Such hyperbranched polymers hold promise as new generation tracking and targeting MRI contrast agents.Entities:
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Year: 2010 PMID: 20345132 DOI: 10.1021/ja100252y
Source DB: PubMed Journal: J Am Chem Soc ISSN: 0002-7863 Impact factor: 15.419