| Literature DB >> 2034239 |
M Sasiadek1, H Järventaus, M Sorsa.
Abstract
Sister-chromatid exchanges (SCEs) were analyzed in CHO cells after pulse treatment with 1,3-butadiene, 3,4-epoxy-1-butene (monoepoxybutene) and 1,2:3,4-diepoxybutane (diepoxybutane). A weak dose effect was observed after exposure to 1,3-butadiene but only in the presence of S9 mix. Monoepoxybutene and diepoxybutane were highly effective in inducing SCEs at concentrations of 0.1-1 microM both in the presence and in the absence of S9 mix. At higher concentrations the response was more pronounced without S9 mix.Entities:
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Year: 1991 PMID： 2034239 DOI： 10.1016/0165-7992(91)90033-z
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433