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Literature DB >> 20339997

The evidence for adjuvant treatment of elderly patients (age > or = 70) with stage III colon cancer is inconclusive.

Kok-Yang Tan¹, Fumio Konishi, Koichi Suzuki.

Abstract

This article critically discusses the current evidence for adjuvant chemotherapy in elderly patients (> or =70 years of age) with stage III colon cancer. The authors emphasize that current evidence is inconclusive, and surgeons should be aware of this fact when making informed decisions and recommendations.

Entities: Disease Species

Mesh：

Year: 2010 PMID： 20339997 DOI： 10.1007/s00595-009-4047-0

Source DB: PubMed Journal: Surg Today ISSN： 0941-1291 Impact factor: 2.549

16 in total

1. A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients.

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Journal: N Engl J Med Date: 2001-10-11 Impact factor: 91.245

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Journal: JAMA Date: 2005-12-07 Impact factor: 56.272

3. Survival associated with 5-fluorouracil-based adjuvant chemotherapy among elderly patients with node-positive colon cancer.

Authors: Vijaya Sundararajan; Nandita Mitra; Judith S Jacobson; Victor R Grann; Daniel F Heitjan; Alfred I Neugut
Journal: Ann Intern Med Date: 2002-03-05 Impact factor: 25.391

Review 4. Adjuvant therapy in the elderly: making the right decision.

Authors: Hyman B Muss; Laura Biganzoli; Daniel J Sargent; Matti Aapro
Journal: J Clin Oncol Date: 2007-05-10 Impact factor: 44.544

Review 5. Colon cancer: update on adjuvant therapy.

Authors: Max S Mano; François Duhoux
Journal: Clin Colorectal Cancer Date: 2008-05 Impact factor: 4.481

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Journal: Cancer Date: 1998-06-01 Impact factor: 6.860

7. Efficacy of a continuous venous infusion of fluorouracil and daily divided dose cisplatin as adjuvant therapy in resectable colorectal cancer: a prospective randomized trial.

Authors: Fumitake Hata; Kazuaki Sasaki; Koichi Hirata; Susumu Yamamitsu; Tetsuhiko Shirasaka
Journal: Surg Today Date: 2008-07-09 Impact factor: 2.549

8. Effectiveness of adjuvant fluorouracil in clinical practice: a population-based cohort study of elderly patients with stage III colon cancer.

Authors: Theodore J Iwashyna; Elizabeth B Lamont
Journal: J Clin Oncol Date: 2002-10-01 Impact factor: 44.544

9. Usefulness of frailty markers in the assessment of the health and functional status of older cancer patients referred for chemotherapy: a pilot study.

Authors: Frederique Retornaz; Johanne Monette; Gerald Batist; Michèle Monette; Nadia Sourial; David Small; Stephen Caplan; Doreen Wan-Chow-Wah; Martine T E Puts; Howard Bergman
Journal: J Gerontol A Biol Sci Med Sci Date: 2008-05 Impact factor: 6.053

10. Folinic acid and 5-fluorouracil as adjuvant chemotherapy in colon cancer.

Authors: G Francini; R Petrioli; L Lorenzini; S Mancini; S Armenio; G Tanzini; S Marsili; A Aquino; G Marzocca; S Civitelli
Journal: Gastroenterology Date: 1994-04 Impact factor: 22.682

1 in total

Review 1. Optimizing the management of elderly colorectal surgery patients.

Authors: Kok-Yang Tan; Fumio Konishi; Lawrence Tan; Wui-Kin Chin; Hean-Yee Ong; Phyllis Tan
Journal: Surg Today Date: 2010-11-03 Impact factor: 2.549

1 in total