Literature DB >> 20335655

Epithelial-mesenchymal transitions and hepatocarcinogenesis.

Janice Jou1, Anna Mae Diehl.   

Abstract

Epithelial-mesenchymal transitions (EMTs) are believed to play a role in invasion and metastasis of many types of tumors. In this issue of the JCI, Chen et al. show that a gene that has been associated with aggressive biology in hepatocellular carcinomas initiates a molecular cascade that results in EMT.

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Year:  2010        PMID： 20335655      PMCID： PMC2846072          DOI： 10.1172/JCI42615

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  30 in total

1.  CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients.

Authors:  Leilei Chen; Tim Hon Man Chan; Yun-Fei Yuan; Liang Hu; Jun Huang; Stephanie Ma; Jian Wang; Sui-Sui Dong; Kwan Ho Tang; Dan Xie; Yan Li; Xin-Yuan Guan
Journal:  J Clin Invest       Date:  2010-03-24       Impact factor: 14.808

2.  Blockade of four-transmembrane L6 family member 5 (TM4SF5)-mediated tumorigenicity in hepatocytes by a synthetic chalcone derivative.

Authors:  Sin-Ae Lee; Hyung Won Ryu; Young Mee Kim; Suyong Choi; Mi Ji Lee; Tae Kyoung Kwak; Hyeon Jung Kim; Moonjae Cho; Ki Hun Park; Jung Weon Lee
Journal:  Hepatology       Date:  2009-04       Impact factor: 17.425

3.  Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma.

Authors:  Dong-Jiang Tang; Sui-Sui Dong; Ning-Fang Ma; Dan Xie; Leilei Chen; Li Fu; Sze Hang Lau; Yan Li; Yan Li; Xin-Yuan Guan
Journal:  Hepatology       Date:  2010-04       Impact factor: 17.425

Review 4.  Rho GTPases and the control of cell behaviour.

Authors:  A Hall
Journal:  Biochem Soc Trans       Date:  2005-11       Impact factor: 5.407

5.  The epithelial-to-mesenchymal transition in liver fibrosis: here today, gone tomorrow?

Authors:  Rebecca G Wells
Journal:  Hepatology       Date:  2010-03       Impact factor: 17.425

6.  Hypoxia-induced des-gamma-carboxy prothrombin production in hepatocellular carcinoma.

Authors:  Kazumoto Murata; Hideto Suzuki; Hiroshi Okano; Takashi Oyamada; Yoshikazu Yasuda; Atsushi Sakamoto
Journal:  Int J Oncol       Date:  2010-01       Impact factor: 5.650

Review 7.  Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review).

Authors:  Yuriko Katoh; Masaru Katoh
Journal:  Int J Mol Med       Date:  2008-09       Impact factor: 4.101

Review 8.  Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.

Authors:  Y Katoh; M Katoh
Journal:  Curr Mol Med       Date:  2009-09       Impact factor: 2.222

Review 9.  The basics of epithelial-mesenchymal transition.

Authors:  Raghu Kalluri; Robert A Weinberg
Journal:  J Clin Invest       Date:  2009-06       Impact factor: 14.808

10.  Hepatic wound repair.

Authors:  Maurizio Parola; Massimo Pinzani
Journal:  Fibrogenesis Tissue Repair       Date:  2009-09-25
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  43 in total

1.  pIgR: frenemy of inflammation, EMT, and HCC progression.

Authors:  Nathalie Sphyris; Sendurai A Mani
Journal:  J Natl Cancer Inst       Date:  2011-10-24       Impact factor: 13.506

2.  MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis.

Authors:  Keun Hur; Yuji Toiyama; Masanobu Takahashi; Francesc Balaguer; Takeshi Nagasaka; Junichi Koike; Hiromichi Hemmi; Minoru Koi; C Richard Boland; Ajay Goel
Journal:  Gut       Date:  2012-06-26       Impact factor: 23.059

3.  Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma.

Authors:  Takahiro Kodama; Justin Y Newberg; Michiko Kodama; Roberto Rangel; Kosuke Yoshihara; Jean C Tien; Pamela H Parsons; Hao Wu; Milton J Finegold; Neal G Copeland; Nancy A Jenkins
Journal:  Proc Natl Acad Sci U S A       Date:  2016-05-31       Impact factor: 11.205

4.  High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma.

Authors:  Xinghua Zhu; Yaxun Wu; Xiaobing Miao; Chunsun Li; Haibing Yin; Shuyun Yang; Xiaoyun Lu; Yushan Liu; Yali Chen; Rong Shen; Xudong Chen; Song He
Journal:  Tumour Biol       Date:  2016-09-12

5.  Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma.

Authors:  Naoki Oishi; Mia R Kumar; Stephanie Roessler; Junfang Ji; Marshonna Forgues; Anuradha Budhu; Xuelian Zhao; Jesper B Andersen; Qing-Hai Ye; Hu-Liang Jia; Lun-Xiu Qin; Taro Yamashita; Hyun Goo Woo; Yoon Jun Kim; Shuichi Kaneko; Zhao-You Tang; Snorri S Thorgeirsson; Xin Wei Wang
Journal:  Hepatology       Date:  2012-08-22       Impact factor: 17.425

6.  Network modeling of TGFβ signaling in hepatocellular carcinoma epithelial-to-mesenchymal transition reveals joint sonic hedgehog and Wnt pathway activation.

Authors:  Steven Nathaniel Steinway; Jorge G T Zañudo; Wei Ding; Carl Bart Rountree; David J Feith; Thomas P Loughran; Reka Albert
Journal:  Cancer Res       Date:  2014-09-04       Impact factor: 12.701

7.  Decreased expression and prognostic role of mitogen-activated protein kinase phosphatase 4 in hepatocellular carcinoma.

Authors:  Jinxia Liu; Wenkai Ni; Mingbing Xiao; Feng Jiang; Runzhou Ni
Journal:  J Gastrointest Surg       Date:  2013-01-17       Impact factor: 3.452

8.  Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma.

Authors:  Isaac S Chan; Cynthia D Guy; Yuping Chen; Jiuyi Lu; Marzena Swiderska-Syn; Gregory A Michelotti; Gamze Karaca; Guanhua Xie; Leandi Krüger; Wing-Kin Syn; Blair R Anderson; Thiago A Pereira; Steve S Choi; Albert S Baldwin; Anna Mae Diehl
Journal:  Cancer Res       Date:  2012-10-12       Impact factor: 12.701

Review 9.  An update on microRNAs as colorectal cancer biomarkers: where are we and what's next?

Authors:  Yoshinaga Okugawa; Yuji Toiyama; Ajay Goel
Journal:  Expert Rev Mol Diagn       Date:  2014-08-28       Impact factor: 5.225

10.  Circulating microRNA-203 predicts metastases, early recurrence, and poor prognosis in human gastric cancer.

Authors:  Hiroki Imaoka; Yuji Toiyama; Masato Okigami; Hiromi Yasuda; Susumu Saigusa; Masaki Ohi; Koji Tanaka; Yasuhiro Inoue; Yasuhiko Mohri; Masato Kusunoki
Journal:  Gastric Cancer       Date:  2015-08-02       Impact factor: 7.370
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