OBJECTIVES: We designed this study to assess the potential effects of physical activity and dietary habits on glucose tolerance during pregnancy. METHODS: This is an observational study involving 268 women who underwent a 50-g oral glucose challenge test (GCT) at 27±6.9 week of gestation. Plasma glucose level at 1-h GCT ≥ 140 mg/dl was used to define abnormal glucose tolerance (AGT). Physical activity was evaluated using the short form of the International Physical Activity Questionnaire (IPAQ), while for dietary habits we used a food frequency questionnaire linked to a computerised program. RESULTS: One hundred five women had AGT (AGT+) and 163 had normal glucose tolerance (AGT−). There was no difference between the two groups in demographic and clinical data, with the exception of pre-pregnancy BMI and weight gain both higher in AGT+ women. Also, all parameters referring to physical activity energy and diet (Kcal and diet components) were not statistically different between the two groups. After a multivariate analysis, only pre-pregnancy BMI (F-value 9.264, p=0.002) remained an independent predictor of 1-h plasma glucose. CONCLUSIONS: Our study suggests that high pre-pregnancy BMI confers a substantially high risk of AGT, independently of lifestyle during pregnancy.
OBJECTIVES: We designed this study to assess the potential effects of physical activity and dietary habits on glucose tolerance during pregnancy. METHODS: This is an observational study involving 268 women who underwent a 50-g oral glucose challenge test (GCT) at 27±6.9 week of gestation. Plasma glucose level at 1-h GCT ≥ 140 mg/dl was used to define abnormal glucose tolerance (AGT). Physical activity was evaluated using the short form of the International Physical Activity Questionnaire (IPAQ), while for dietary habits we used a food frequency questionnaire linked to a computerised program. RESULTS: One hundred five women had AGT (AGT+) and 163 had normal glucose tolerance (AGT−). There was no difference between the two groups in demographic and clinical data, with the exception of pre-pregnancy BMI and weight gain both higher in AGT+women. Also, all parameters referring to physical activity energy and diet (Kcal and diet components) were not statistically different between the two groups. After a multivariate analysis, only pre-pregnancy BMI (F-value 9.264, p=0.002) remained an independent predictor of 1-h plasma glucose. CONCLUSIONS: Our study suggests that high pre-pregnancy BMI confers a substantially high risk of AGT, independently of lifestyle during pregnancy.
Authors: Sara Wilcox; Jihong Liu; Cheryl L Addy; Gabrielle Turner-McGrievy; Judith T Burgis; Ellen Wingard; Alicia A Dahl; Kara M Whitaker; Lara Schneider; Alycia K Boutté Journal: Contemp Clin Trials Date: 2018-01-31 Impact factor: 2.226
Authors: L Chasan-Taber; M Silveira; K E Lynch; P Pekow; B Braun; J E Manson; C G Solomon; G Markenson Journal: Diabetes Metab Date: 2013-10-22 Impact factor: 6.041