Literature DB >> 20331514

Liver retransplantation in children: the Atlanta experience.

Thomas G Heffron1, Todd Pillen, Gregory Smallwood, Stuart Henry, Sundari Sekar, David Solis, Katherine Casper, Carlos Fasola, Rene Romero.   

Abstract

Liver retransplantation is routinely offered at our institution. Previous reports document that patient and graft survival is significantly less after pediatric rLT compared to primary LT. This has engendered intense debate regarding optimal allocation of organs. Here, we examine our program's approach to pediatric hepatic retransplantation related to patient factors affecting outcomes. Between 1997 and 2009, 272 LTs were performed in 234 patients (mean survival 1994 +/- 1367 days) at our center. Thirty-four patients required rLT including 10 who received their primary transplant elsewhere and four who required two retransplantations. Patient survival did not differ significantly between rLT and LT at one and three yr (p = 0.56). Graft survival between rLT and LT was also similar (p = 0.606) at one and three yr. No significant difference in graft or patient survival was noted between: Patients retransplanted <30 days after LT vs. those >30 days (p = 0.152); patients transplanted with technical variants vs. whole grafts (p = 0.966); technical variants utilized for LT vs. rLT (p = 0.713); rLT recipient age (< or >5 yr; p = 0.298); or ABOI for rLT and LT (p = 0.650). Retransplantation should be offered to optimize pediatric recipient survival after LT and offers similar survival as primary transplant.

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Year:  2010        PMID: 20331514     DOI: 10.1111/j.1399-3046.2010.01304.x

Source DB:  PubMed          Journal:  Pediatr Transplant        ISSN: 1397-3142


  2 in total

1.  Over 30 Years of Pediatric Liver Transplantation at the Charité-Universitätsmedizin Berlin.

Authors:  Simon Moosburner; Leke Wiering; Safak Gül-Klein; Paul Ritschl; Tomasz Dziodzio; Nathanael Raschzok; Christian Witzel; Alexander Gratopp; Stephan Henning; Philip Bufler; Moritz Schmelzle; Georg Lurje; Wenzel Schöning; Johann Pratschke; Brigitta Globke; Robert Öllinger
Journal:  J Clin Med       Date:  2022-02-09       Impact factor: 4.241

2.  The outcomes of pediatric liver retransplantation from a living donor: a 17-year single-center experience.

Authors:  Kohei Miura; Seisuke Sakamoto; Keita Shimata; Masaki Honda; Takashi Kobayashi; Toshifumi Wakai; Yasuhiko Sugawara; Yukihiro Inomata
Journal:  Surg Today       Date:  2017-04-22       Impact factor: 2.549

  2 in total

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