Literature DB >> 2032367

Malignant tumours of the middle ear.

D L Savić1, D R Djerić.   

Abstract

The authors present 15 patients with middle ear malignant tumours, of which 13 were squamous cell carcinomas, one was a rhabdomyosarcoma and one a malignant lymphoma. In 11 of 13 patients with squamous cell carcinoma, long-standing chronic otitis media preceded the malignant process and only in 2 patients did the tumour develop without previous chronic infection. Most of the patients presented at an advanced stage of the disease: in 6 the tumour had destroyed surrounding bone, commonly involving the endocranium; in 7 the facial nerve was paralysed and in 8 patients there was total hearing loss. The diagnosis of malignant tumour was established before surgery in 5 patients, but 8 patients were operated upon for suspected chronic otitis. Three patients died without treatment and 10 were treated: 3 with radiotherapy because the tumour was inoperable, 3 had surgery only and 4 patients had surgery and received radiotherapy post-operatively. Of 7 operated patients only 2 are alive without signs of tumour. Our findings suggest that otologists should bear in mind this disease in patients with chronic suppurative otitis and accompanying suspected symptoms. In 2 patients with rare types of sarcoma of the middle ear the diagnosis of tumour was established at an advanced stage and they could not be treated.

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Year:  1991        PMID: 2032367     DOI: 10.1111/j.1365-2273.1991.tb01949.x

Source DB:  PubMed          Journal:  Clin Otolaryngol Allied Sci        ISSN: 0307-7772


  2 in total

1.  Detection of Epstein-Barr and Human Papilloma Viruses in the Middle Ear Squamous Cell Carcinoma.

Authors:  Agus Surono; Bambang Hariwiyanto; Edhie Samodra
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2016-05-07

2.  Prevalence of human papillomavirus in middle ear carcinoma associated with chronic otitis media.

Authors:  Y T Jin; S T Tsai; C Li; K C Chang; J J Yan; W Y Chao; H L Eng; T Y Chou; T C Wu; I J Su
Journal:  Am J Pathol       Date:  1997-04       Impact factor: 4.307

  2 in total

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