Literature DB >> 20308177

varLD: a program for quantifying variation in linkage disequilibrium patterns between populations.

Rick Twee-Hee Ong1, Yik-Ying Teo.   

Abstract

MOTIVATION: Linkage disequilibrium (LD) differences between populations can potentially result in failure to replicate primary signals of trait association in independent genome-wide association studies (GWAS). However, such inter-population LD differences can be leveraged to narrow the search for common causal variants responsible for the association signals observed. The ability to assess and quantify LD variations among populations is thus expected to contribute to both replication and fine-mapping stages of GWAS. AVAILABILITY: The program varLD is available for download from http://www.nus-cme.org.sg/software/varld.html.

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Year:  2010        PMID： 20308177     DOI： 10.1093/bioinformatics/btq125

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


  39 in total

1.  Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.

Authors:  Young Jin Kim; Min Jin Go; Cheng Hu; Chang Bum Hong; Yun Kyoung Kim; Ji Young Lee; Joo-Yeon Hwang; Ji Hee Oh; Dong-Joon Kim; Nam Hee Kim; Soeui Kim; Eun Jung Hong; Ji-Hyun Kim; Haesook Min; Yeonjung Kim; Rong Zhang; Weiping Jia; Yukinori Okada; Atsushi Takahashi; Michiaki Kubo; Toshihiro Tanaka; Naoyuki Kamatani; Koichi Matsuda; Taesung Park; Bermseok Oh; Kuchan Kimm; Daehee Kang; Chol Shin; Nam H Cho; Hyung-Lae Kim; Bok-Ghee Han; Jong-Young Lee; Yoon Shin Cho
Journal:  Nat Genet       Date:  2011-09-11       Impact factor: 38.330

2.  A survey of sub-Saharan gene flow into the Mediterranean at risk loci for coronary artery disease.

Authors:  Miguel M Álvarez-Álvarez; Daniela Zanetti; Robert Carreras-Torres; Pedro Moral; Georgios Athanasiadis
Journal:  Eur J Hum Genet       Date:  2017-01-18       Impact factor: 4.246

3.  Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.

Authors:  Norihiro Kato; Fumihiko Takeuchi; Yasuharu Tabara; Tanika N Kelly; Min Jin Go; Xueling Sim; Wan Ting Tay; Chien-Hsiun Chen; Yi Zhang; Ken Yamamoto; Tomohiro Katsuya; Mitsuhiro Yokota; Young Jin Kim; Rick Twee Hee Ong; Toru Nabika; Dongfeng Gu; Li-Ching Chang; Yoshihiro Kokubo; Wei Huang; Keizo Ohnaka; Yukio Yamori; Eitaro Nakashima; Cashell E Jaquish; Jong-Young Lee; Mark Seielstad; Masato Isono; James E Hixson; Yuan-Tsong Chen; Tetsuro Miki; Xueya Zhou; Takao Sugiyama; Jae-Pil Jeon; Jian Jun Liu; Ryoichi Takayanagi; Sung Soo Kim; Tin Aung; Yun Ju Sung; Xuegong Zhang; Tien Yin Wong; Bok-Ghee Han; Shotai Kobayashi; Toshio Ogihara; Dingliang Zhu; Naoharu Iwai; Jer-Yuarn Wu; Yik Ying Teo; E Shyong Tai; Yoon Shin Cho; Jiang He
Journal:  Nat Genet       Date:  2011-05-15       Impact factor: 38.330

4.  Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci.

Authors:  Tanika N Kelly; Fumihiko Takeuchi; Yasuharu Tabara; Todd L Edwards; Young Jin Kim; Peng Chen; Huaixing Li; Ying Wu; Chi-Fan Yang; Yonghong Zhang; Dongfeng Gu; Tomohiro Katsuya; Takayoshi Ohkubo; Yu-Tang Gao; Min Jin Go; Yik Ying Teo; Ling Lu; Nanette R Lee; Li-Ching Chang; Hao Peng; Qi Zhao; Eitaro Nakashima; Yoshikuni Kita; Xiao-Ou Shu; Nam Hee Kim; E Shyong Tai; Yiqin Wang; Linda S Adair; Chien-Hsiun Chen; Shihiu Zhang; Changwei Li; Toru Nabika; Satoshi Umemura; Qiuyin Cai; Yoon Shin Cho; Tien Yin Wong; Jingwen Zhu; Jer-Yuarn Wu; Xin Gao; James E Hixson; Hui Cai; Juyoung Lee; Ching-Yu Cheng; Dabeeru C Rao; Yong-Bing Xiang; Myeong-Chan Cho; Bok-Ghee Han; Aili Wang; Fuu-Jen Tsai; Karen Mohlke; Xu Lin; Mohammad Kamran Ikram; Jong-Young Lee; Wei Zheng; Miki Tetsuro; Norihiro Kato; Jiang He
Journal:  Hypertension       Date:  2013-09-03       Impact factor: 10.190

Review 5.  Pharmacogenetics of drug-metabolizing enzymes in US Hispanics.

Authors:  Karla Claudio-Campos; Jorge Duconge; Carmen L Cadilla; Gualberto Ruaño
Journal:  Drug Metab Pers Ther       Date:  2015-06

6.  Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource.

Authors:  C-T Liu; M C Y Ng; D Rybin; A Adeyemo; S J Bielinski; E Boerwinkle; I Borecki; B Cade; Y D I Chen; L Djousse; M Fornage; M O Goodarzi; S F A Grant; X Guo; T Harris; E Kabagambe; J R Kizer; Y Liu; K L Lunetta; K Mukamal; J A Nettleton; J S Pankow; S R Patel; E Ramos; L Rasmussen-Torvik; S S Rich; C N Rotimi; D Sarpong; D Shriner; M Sims; J M Zmuda; S Redline; W H Kao; D Siscovick; J C Florez; J I Rotter; J Dupuis; J G Wilson; D W Bowden; J B Meigs
Journal:  Diabetologia       Date:  2012-08-16       Impact factor: 10.122

7.  A meta-analysis of genome-wide association studies of asthma in Puerto Ricans.

Authors:  Qi Yan; John Brehm; Maria Pino-Yanes; Erick Forno; Jerome Lin; Sam S Oh; Edna Acosta-Perez; Cathy C Laurie; Michelle M Cloutier; Benjamin A Raby; Adrienne M Stilp; Tamar Sofer; Donglei Hu; Scott Huntsman; Celeste S Eng; Matthew P Conomos; Deepa Rastogi; Kenneth Rice; Glorisa Canino; Wei Chen; R Graham Barr; Esteban G Burchard; Juan C Celedón
Journal:  Eur Respir J       Date:  2017-05-01       Impact factor: 16.671

8.  High-throughput single-nucleotide polymorphism discovery and the search for candidate genes for long-term SIVmac nonprogression in Chinese rhesus macaques (Macaca mulatta).

Authors:  J Satkoski Trask; W T Garnica; R S Malhi; S Kanthaswamy; D G Smith
Journal:  J Med Primatol       Date:  2011-08       Impact factor: 0.667

9.  Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

Authors:  Daphna Weissglas-Volkov; Carlos A Aguilar-Salinas; Elina Nikkola; Kerry A Deere; Ivette Cruz-Bautista; Olimpia Arellano-Campos; Linda Liliana Muñoz-Hernandez; Lizeth Gomez-Munguia; Maria Luisa Ordoñez-Sánchez; Prasad M V Linga Reddy; Aldons J Lusis; Niina Matikainen; Marja-Riitta Taskinen; Laura Riba; Rita M Cantor; Janet S Sinsheimer; Teresa Tusie-Luna; Päivi Pajukanta
Journal:  J Med Genet       Date:  2013-03-15       Impact factor: 6.318

10.  Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.

Authors:  Jaspal S Kooner; Danish Saleheen; Xueling Sim; Joban Sehmi; Weihua Zhang; Philippe Frossard; Latonya F Been; Kee-Seng Chia; Antigone S Dimas; Neelam Hassanali; Tazeen Jafar; Jeremy B M Jowett; Xinzhong Li; Venkatesan Radha; Simon D Rees; Fumihiko Takeuchi; Robin Young; Tin Aung; Abdul Basit; Manickam Chidambaram; Debashish Das; Elin Grundberg; Asa K Hedman; Zafar I Hydrie; Muhammed Islam; Chiea-Chuen Khor; Sudhir Kowlessur; Malene M Kristensen; Samuel Liju; Wei-Yen Lim; David R Matthews; Jianjun Liu; Andrew P Morris; Alexandra C Nica; Janani M Pinidiyapathirage; Inga Prokopenko; Asif Rasheed; Maria Samuel; Nabi Shah; A Samad Shera; Kerrin S Small; Chen Suo; Ananda R Wickremasinghe; Tien Yin Wong; Mingyu Yang; Fan Zhang; Goncalo R Abecasis; Anthony H Barnett; Mark Caulfield; Panos Deloukas; Timothy M Frayling; Philippe Froguel; Norihiro Kato; Prasad Katulanda; M Ann Kelly; Junbin Liang; Viswanathan Mohan; Dharambir K Sanghera; James Scott; Mark Seielstad; Paul Z Zimmet; Paul Elliott; Yik Ying Teo; Mark I McCarthy; John Danesh; E Shyong Tai; John C Chambers
Journal:  Nat Genet       Date:  2011-08-28       Impact factor: 38.330
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