Literature DB >> 20307427

Treatment of tinea pedis with socks containing copper-oxide impregnated fibers.

Richard C Zatcoff1, Michael S Smith, Gadi Borkow.   

Abstract

BACKGROUND: Tinea pedis, known as Athlete's foot, is a common fungal infection of the feet, the majority of cases caused by dermatophytes. Copper oxide has potent antimicrobial and antifungal properties.
OBJECTIVE: A pilot study designed to examine the efficacy of treating tinea pedis utilizing copper-oxide impregnated fibers woven into socks worn on a daily basis.
METHODS: Fifty-six patients, ranging in age from 21 to 85 years were clinically diagnosed, photographed, and treated with the copper soled socks. Eight variables were studied, including scaling, erythema, fissuring, burning or itching, vesicular eruptions, edema, odor, and drainage.
RESULTS: In a 9-day average follow up, all patients showed improvement or resolution of erythema (with a 95% Confidence interval (CI) of 1.0), fissuring (CI=1.0), vesicular eruptions (CI=1.0), scaling (CI=0.9-1.0) and for burning and itching (CI=0.61-0.95). In a 40-day average follow up, the 95% CI for improvement or resolution of scaling was 0.68-0.97, for erythema, 0.65-0.97, and for fissuring, burning and itching and vesicular eruptions it was 1.0. None of the study subjects worsened or showed adverse reactions while wearing copper-oxide impregnated socks.
CONCLUSION: This study strongly supports the effectiveness in using copper-oxide impregnated polyester fibers in treating the common manifestations of tinea pedis.

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Year:  2008        PMID: 20307427     DOI: 10.1016/j.foot.2008.03.005

Source DB:  PubMed          Journal:  Foot (Edinb)        ISSN: 0958-2592


  10 in total

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Journal:  J Mater Sci Mater Med       Date:  2017-02-01       Impact factor: 3.896

Review 2.  The Use of Copper as an Antimicrobial Agent in Health Care, Including Obstetrics and Gynecology.

Authors:  Linda P Arendsen; Ranee Thakar; Abdul H Sultan
Journal:  Clin Microbiol Rev       Date:  2019-08-14       Impact factor: 26.132

Review 3.  A Paradigm Shift in the Treatment and Management of Onychomycosis.

Authors:  Aditya K Gupta; Maanasa Venkataraman; Helen J Renaud; Richard Summerbell; Neil H Shear; Vincent Piguet
Journal:  Skin Appendage Disord       Date:  2021-05-11

4.  A novel anti-influenza copper oxide containing respiratory face mask.

Authors:  Gadi Borkow; Steve S Zhou; Tom Page; Jeffrey Gabbay
Journal:  PLoS One       Date:  2010-06-25       Impact factor: 3.240

5.  Activation of Erk and p53 regulates copper oxide nanoparticle-induced cytotoxicity in keratinocytes and fibroblasts.

Authors:  Cheng Luo; Yan Li; Liang Yang; Yan Zheng; Jiangang Long; Jinjing Jia; Shengxiang Xiao; Jiankang Liu
Journal:  Int J Nanomedicine       Date:  2014-10-10

6.  SILAC-based quantitative proteomic analysis of human lung cell response to copper oxide nanoparticles.

Authors:  Mariola J Edelmann; Leslie A Shack; Caitlin D Naske; Keisha B Walters; Bindu Nanduri
Journal:  PLoS One       Date:  2014-12-03       Impact factor: 3.240

7.  Effectiveness of a Central Discharge Element Sock for Plantar Temperature Reduction and Improving Comfort.

Authors:  Alfonso Martínez-Nova; Víctor Manuel Jiménez-Cano; Juan Miguel Caracuel-López; Beatriz Gómez-Martín; Elena Escamilla-Martínez; Raquel Sánchez-Rodríguez
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Review 8.  Development of copper based drugs, radiopharmaceuticals and medical materials.

Authors:  Paweł Szymański; Tomasz Frączek; Magdalena Markowicz; Elżbieta Mikiciuk-Olasik
Journal:  Biometals       Date:  2012-08-23       Impact factor: 2.949

9.  Using Copper to Improve the Well-Being of the Skin.

Authors:  Gadi Borkow
Journal:  Curr Chem Biol       Date:  2014-08

10.  Dermatology within the UK podiatric literature: a content analysis (1989-2010).

Authors:  Ivan R Bristow; Alan M Borthwick
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  10 in total

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