| Literature DB >> 20307086 |
Guo-An Zou1, Gang Ding, Zhi-Heng Su, Jun-Shan Yang, Hone-Wu Zhang, Chao-Zhong Peng, Haiji Akber Aisa, Zhong-Mei Zou.
Abstract
Six new cembranoids, laevigatlactones A-F (1-6), and the known compound neocrotocembraneic acid (7) were isolated from leaves of Croton laevigatus. Their structures were elucidated on the basis of spectroscopic analysis, and that of 1 was confirmed by X-ray crystallography. Compound 2 exhibited modest cytotoxicity against HeLa cells, with an IC(50) value of 38.4 microM.Entities:
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Year: 2010 PMID： 20307086 DOI： 10.1021/np100044t
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050