Literature DB >> 20306066

Treatment of vocal fold scar by carbon dioxide laser and collagen injection: retrospective study on 12 patients.

Angels Martínez Arias1, Marc Remacle, Georges Lawson.   

Abstract

Vocal fold scars are the result of injury to the vocal fold lamina propria. This condition leads to an impaired vibration and usually to poor voice quality. The purpose of our study was to compare the pre- and posttreatment voice assessment scores in patients treated by CO(2) laser-assisted freeing of the scar followed by collagen injection. A group of 12 patients (10 women and 2 men) with vocal fold scars was studied retrospectively. Voice assessment was based on stroboscopy and on perceptual scores using the Grade (G) of the GRABS scale, subjective evaluation by the use of the Voice Handicap Index (VHI), aerodynamic measurements [maximum phonation time (MPT) and phonation quotient (PQ)], and acoustical measurements (frequency range and low intensity). Stroboscopy showed an improvement on the mucosal vocal fold wave and on the glottic competence. The mean VHI was improved from 63.16 to 45.5; G from 2 to 1.41; MPT from 7.05 to 8.62 s; and PQ from 463.02 to 358.54 ml/s. CO(2) laser freeing of vocal fold scars followed by collagen injection, combined with speech therapy, improved significantly the aerodynamic parameters (efficiency of voice), but not the acoustical scores.

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Year:  2010        PMID: 20306066     DOI: 10.1007/s00405-010-1231-1

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  17 in total

1.  Use of injectable autologous collagen for correcting glottic gaps: initial results.

Authors:  M Remacle; G Lawson; J Keghian; J Jamart
Journal:  J Voice       Date:  1999-06       Impact factor: 2.009

Review 2.  Vocal fold scar: evaluation and treatment.

Authors:  C A Rosen
Journal:  Otolaryngol Clin North Am       Date:  2000-10       Impact factor: 3.346

3.  Interstitial protein alterations in rabbit vocal fold with scar.

Authors:  Susan L Thibeault; Diane M Bless; Steven D Gray
Journal:  J Voice       Date:  2003-09       Impact factor: 2.009

Review 4.  Current treatment of vocal fold scarring.

Authors:  Shigeru Hirano
Journal:  Curr Opin Otolaryngol Head Neck Surg       Date:  2005-06       Impact factor: 2.064

Review 5.  Current understanding and review of the literature: vocal fold scarring.

Authors:  Jennifer K Hansen; Susan L Thibeault
Journal:  J Voice       Date:  2005-06-20       Impact factor: 2.009

6.  Autologous fat implantation for vocal fold scar: a preliminary report.

Authors:  R T Sataloff; J R Spiegel; M Hawkshaw; D C Rosen; R J Heuer
Journal:  J Voice       Date:  1997-06       Impact factor: 2.009

7.  Management of vocal fold scar with autologous fat implantation: perceptual results.

Authors:  M C Neuenschwander; R T Sataloff; M M Abaza; M J Hawkshaw; D Reiter; J R Spiegel
Journal:  J Voice       Date:  2001-06       Impact factor: 2.009

8.  Viscoelastic and histologic properties in scarred rabbit vocal folds after mesenchymal stem cell injection.

Authors:  S Hertegård; J Cedervall; B Svensson; K Forsberg; F H J Maurer; D Vidovska; P Olivius; L Ahrlund-Richter; K Le Blanc
Journal:  Laryngoscope       Date:  2006-07       Impact factor: 3.325

Review 9.  Results with collagen injection into the vocal folds for medialization.

Authors:  Marc Remacle; Georges Lawson
Journal:  Curr Opin Otolaryngol Head Neck Surg       Date:  2007-06       Impact factor: 2.064

10.  Injection of embryonic stem cells into scarred rabbit vocal folds enhances healing and improves viscoelasticity: short-term results.

Authors:  Jessica Cedervall; Lars Ahrlund-Richter; Bengt Svensson; Kristina Forsgren; Franz H J Maurer; Daniela Vidovska; Stellan Hertegård
Journal:  Laryngoscope       Date:  2007-11       Impact factor: 3.325

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  7 in total

1.  [Treatment of glottal gap].

Authors:  S Voigt-Zimmermann; C Arens
Journal:  HNO       Date:  2013-02       Impact factor: 1.284

Review 2.  Vocal fold scars: current concepts and future directions. Consensus report of the Phonosurgery Committee of the European Laryngological Society.

Authors:  G Friedrich; F G Dikkers; C Arens; M Remacle; M Hess; A Giovanni; S Duflo; A Hantzakos; V Bachy; M Gugatschka
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-04-21       Impact factor: 2.503

3.  Nanoparticle delivery of RNA-based therapeutics to alter the vocal fold tissue response to injury.

Authors:  Nao Hiwatashi; Iv Kraja; Peter A Benedict; Gregory R Dion; Renjie Bing; Bernard Rousseau; Milan R Amin; Danielle M Nalband; Kent Kirshenbaum; Ryan C Branski
Journal:  Laryngoscope       Date:  2017-12-14       Impact factor: 3.325

4.  Prospective multi-arm evaluation of surgical treatments for vocal fold scar and pathologic sulcus vocalis.

Authors:  Nathan V Welham; Seong Hee Choi; Seth H Dailey; Charles N Ford; Jack J Jiang; Diane M Bless
Journal:  Laryngoscope       Date:  2011-05-06       Impact factor: 3.325

5.  Radiation fibrosis of the vocal fold: from man to mouse.

Authors:  Michael M Johns; Vasantha Kolachala; Eric Berg; Susan Muller; Frances X Creighton; Ryan C Branski
Journal:  Laryngoscope       Date:  2012-12       Impact factor: 3.325

Review 6.  Diagnostic and therapeutic pitfalls in benign vocal fold diseases.

Authors:  Jörg Bohlender
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2013-12-13

7.  Adipose-Derived Mesenchymal Stem Cells in the Regeneration of Vocal Folds: A Study on a Chronic Vocal Fold Scar.

Authors:  Angelou Valerie; Kalodimou Vassiliki; Messini Irini; Psychalakis Nikolaos; Eleftheria Karampela; Papalois Apostolos
Journal:  Stem Cells Int       Date:  2016-01-06       Impact factor: 5.443

  7 in total

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