Literature DB >> 203060

HLA-D typing with an association of Dw2 and absent immune responses towards herpes simplex (type i) antigen in multiple sclerosis.

D W Paty, H K Cousin, C R Stiller, D W Boucher, J Furesz, K G Warren, L Marchuk, J B Dossetor.   

Abstract

We have confirmed that HLA-Dw2 is increased in MS patients to 47% (normals 20%). Lymphocyte transformation and antibody studies with herpes simplex antigen show that many of the DW2-positive MS patients have low or absent responses. The association of low responses to HSV and the presence of Dw2 is statistically significant at a p value less than 0.01.

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Year:  1977        PMID: 203060

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  1 in total

1.  Alteration of lymphocyte transformation response to herpes simplex virus infection by acyclovir therapy.

Authors:  W E Lafferty; L A Brewer; L Corey
Journal:  Antimicrob Agents Chemother       Date:  1984-12       Impact factor: 5.191

  1 in total

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