Literature DB >> 20305987

Hepatocyte growth factor in synaptic plasticity and Alzheimer's disease.

Shiv Sharma1.   

Abstract

The hepatocyte growth factor (HGF) was initially identified as a protein that promoted growth of hepatocytes. It regulates proliferation and survival of different types of cells. HGF signaling, which is initiated by its binding to a receptor tyrosine kinase, plays critical roles during development. HGF and its receptor are also present in brain cells. This review describes the role of HGF in hippocampal neurons, synaptic plasticity, and the memory impairment condition, Alzheimer's disease.

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Year:  2010        PMID: 20305987      PMCID: PMC5763803          DOI: 10.1100/tsw.2010.49

Source DB:  PubMed          Journal:  ScientificWorldJournal        ISSN: 1537-744X


  9 in total

Review 1.  The brain renin-angiotensin system: a diversity of functions and implications for CNS diseases.

Authors:  John W Wright; Joseph W Harding
Journal:  Pflugers Arch       Date:  2012-04-26       Impact factor: 3.657

2.  Hepatocyte Growth Factor Attenuates the Severity of Status Epilepticus in Kainic Acid-induced Model of Temporal Lobe Epilepsy by Targeting Apoptosis and Astrogliosis.

Authors:  Sobhan Haghani; Nida Jamali-Raeufy; Motahareh Zeinivand; Soraya Mehrabi; Leila Aryan; Javad Fahanik-Babaei
Journal:  Basic Clin Neurosci       Date:  2021-11-01

3.  Synaptic and extrasynaptic location of the receptor tyrosine kinase met during postnatal development in the mouse neocortex and hippocampus.

Authors:  Kathie L Eagleson; Teresa A Milner; Zhihui Xie; Pat Levitt
Journal:  J Comp Neurol       Date:  2013-10-01       Impact factor: 3.215

4.  Importance of the brain Angiotensin system in Parkinson's disease.

Authors:  John W Wright; Joseph W Harding
Journal:  Parkinsons Dis       Date:  2012-11-07

5.  Double-blind, placebo-controlled study of HGF gene therapy in diabetic neuropathy.

Authors:  John A Kessler; A Gordon Smith; Bong-Soo Cha; Sung Hee Choi; James Wymer; Aziz Shaibani; Senda Ajroud-Driss; Aaron Vinik
Journal:  Ann Clin Transl Neurol       Date:  2015-03-05       Impact factor: 4.511

6.  Increase in Blood Levels of Growth Factors Involved in the Neuroplasticity Process by Using an Extremely Low Frequency Electromagnetic Field in Post-stroke Patients.

Authors:  Natalia Cichoń; Michał Bijak; Piotr Czarny; Elżbieta Miller; Ewelina Synowiec; Tomasz Sliwinski; Joanna Saluk-Bijak
Journal:  Front Aging Neurosci       Date:  2018-09-26       Impact factor: 5.750

7.  Reduced HGF/MET Signaling May Contribute to the Synaptic Pathology in an Alzheimer's Disease Mouse Model.

Authors:  Jing Wei; Xiaokuang Ma; Antoine Nehme; Yuehua Cui; Le Zhang; Shenfeng Qiu
Journal:  Front Aging Neurosci       Date:  2022-07-12       Impact factor: 5.702

8.  Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study.

Authors:  Masaaki Hokama; Sugako Oka; Julio Leon; Toshiharu Ninomiya; Hiroyuki Honda; Kensuke Sasaki; Toru Iwaki; Tomoyuki Ohara; Tomio Sasaki; Frank M LaFerla; Yutaka Kiyohara; Yusaku Nakabeppu
Journal:  Cereb Cortex       Date:  2013-04-17       Impact factor: 5.357

9.  Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer's disease.

Authors:  Bryan Maloney; Yokesh Balaraman; Yunlong Liu; Nipun Chopra; Howard J Edenberg; John Kelsoe; John I Nurnberger; Debomoy K Lahiri
Journal:  Sci Rep       Date:  2019-12-04       Impact factor: 4.379

  9 in total

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