Literature DB >> 2030598

The role of transforming growth factor-beta in hematopoiesis. A review.

W C Hooper1.   

Abstract

The role of TGF beta hematopoiesis is currently being defined. It does appear that TGF beta and related polypeptides can modulate and regulate bone marrow and thymic-derived cells throughout their functional life span. The effects of TGF beta are pleiotropic and may depend on (a) cell lineage, (b) specific cellular phenotype, (c) stage of differentiation, (d) immediate microenvironment, (e) other cytokines and (f) cellular function. The understanding of TGF beta and its relationship to other cytokines should not only increase our understanding of hematopoiesis but may also have therapeutic implications.

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Year:  1991        PMID： 2030598     DOI： 10.1016/0145-2126(91)90118-d

Source DB:  PubMed          Journal:  Leuk Res        ISSN： 0145-2126            Impact factor:   3.156


  5 in total

1.  Tumor-derived cytokines induce bone marrow suppressor cells that mediate immunosuppression through transforming growth factor beta.

Authors:  M R Young; M A Wright; M Coogan; M E Young; J Bagash
Journal:  Cancer Immunol Immunother       Date:  1992       Impact factor: 6.968

Review 2.  Myelofibrosis: pathogenesis of myelofibrosis with myeloid metaplasia. French INSERM Research Network on Myelofibrosis with Myeloid Metaplasia.

Authors:  M C Le Bousse-Kerdilès; M C Martyré
Journal:  Springer Semin Immunopathol       Date:  1999

3.  Onset and progression of pathological lesions in transforming growth factor-beta 1-deficient mice.

Authors:  G P Boivin; B A O'Toole; I E Orsmby; R J Diebold; M J Eis; T Doetschman; A B Kier
Journal:  Am J Pathol       Date:  1995-01       Impact factor: 4.307

4.  The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells.

Authors:  M Selvakumaran; H K Lin; R T Sjin; J C Reed; D A Liebermann; B Hoffman
Journal:  Mol Cell Biol       Date:  1994-04       Impact factor: 4.272

Review 5.  Human immunodeficiency virus type 1 (HIV-1) and human hematopoietic progenitor cells.

Authors:  M C Re; G Furlini; G Zauli; M La Placa
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574
  5 in total

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