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Literature DB >> 20305830

Synthesis and structure assignment of the minor metabolite arising from the frog pathogen Mycobacterium liflandii.

Thomas Spangenberg¹, Sylvain Aubry, Yoshito Kishi.

Abstract

Total synthesis and structure assignment of the minor metabolite present in lipid extracts of the frog pathogen Mycobacterium liflandii are reported.

Entities: CellLine Chemical Disease Gene Species

Year: 2010 PMID： 20305830 PMCID： PMC2840265 DOI： 10.1016/j.tetlet.2010.01.105

Source DB: PubMed Journal: Tetrahedron Lett ISSN： 0040-4039 Impact factor: 2.415

24 in total

1. Stereochemistry of the core structure of the mycolactones.

Authors: A B Benowitz; S Fidanze; P L Small; Y Kishi
Journal: J Am Chem Soc Date: 2001-05-30 Impact factor: 15.419

2. Total synthesis of the mycolactones.

Authors: Fengbin Song; Steve Fidanze; Andrew B Benowitz; Yoshito Kishi
Journal: Org Lett Date: 2002-02-21 Impact factor: 6.005

3. Complete structure of the mycolactones.

Authors: S Fidanze; F Song; M Szlosek-Pinaud; P L Small; Y Kishi
Journal: J Am Chem Soc Date: 2001-10-17 Impact factor: 15.419

4. Total Synthesis of Mycolactones A and B.

Authors: Fengbin Song; Steve Fidanze; Andrew B Benowitz; Yoshito Kishi
Journal: Tetrahedron Date: 2007-06-25 Impact factor: 2.457

5. Total synthesis and stereochemistry of mycolactone F.

Authors: Han-Je Kim; Yoshito Kishi
Journal: J Am Chem Soc Date: 2008-01-19 Impact factor: 15.419

6. Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence.

Authors: K M George; D Chatterjee; G Gunawardana; D Welty; J Hayman; R Lee; P L Small
Journal: Science Date: 1999-02-05 Impact factor: 47.728

Review 7. Mycobacterium ulcerans disease.

Authors: Tjip S van der Werf; Ymkje Stienstra; R Christian Johnson; Richard Phillips; Ohene Adjei; Bernhard Fleischer; Mark H Wansbrough-Jones; Paul D R Johnson; Françoise Portaels; Winette T A van der Graaf; Kingsley Asiedu
Journal: Bull World Health Organ Date: 2005-11-10 Impact factor: 9.408

Synthesis and structure assignment of the minor metabolite arising from the frog pathogen Mycobacterium liflandii.

1. Stereochemistry of the core structure of the mycolactones.

2. Total synthesis of the mycolactones.

3. Complete structure of the mycolactones.

4. Total Synthesis of Mycolactones A and B.

5. Total synthesis and stereochemistry of mycolactone F.

6. Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence.

Review 7. Mycobacterium ulcerans disease.

Review 8. Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans.

9. Synthesis and structure of mycolactone E isolated from frog mycobacterium.

Review 10. Mycolactones and Mycobacterium ulcerans disease.

1. Chemistry of mycolactones, the causative toxins of Buruli ulcer.

Review 2. The chemistry and biology of mycolactones.

3. A unified synthetic strategy to the Cryptocarya family of natural products exploiting Anion Relay Chemistry (ARC).