The effect of semantic relatedness on syntactic analysis: An fMRI study.

The sentences we process in normal conversation tend to refer to information that we are familiar with rather than abstract, unrelated information. This allows for the use of knowledge stores to help facilitate comprehension processes. In many sentence comprehension studies, the stimuli are designed such that the use of world knowledge is limited. Here, we investigated how the semantic relatedness of sentence constituents influences sentence processing. A three factor design was employed in which processing phase (sentence vs. probe), syntactic complexity (object-relative vs. conjoined active) and the semantic relatedness of the nouns within the sentence was examined. We found a differential effect in two sub-regions of the left inferior frontal gyrus (LIFG). BA 44 revealed an effect of syntactic complexity while inferior portions of the LIFG (BA 47) revealed an effect of relatedness as well as an interaction between complexity and relatedness during the probe phase. In addition, significant differences in activation were observed when comparing the sentence processing and probe phases with the sentence phase eliciting stronger semantic related activation while the probe phase elicited stronger working memory related activation. Copyright 2010 Elsevier Inc. All rights reserved.