| Literature DB >> 20303444 |
Markus Knuf1, Heinz-Josef Schmitt, Jeanne-Marie Jacquet, Alix Collard, Dorothee Kieninger, Claudius U Meyer, Claire-Anne Siegrist, Fred Zepp.
Abstract
After a birth dose of acellular pertussis (aP) and diphtheria (DT)aP-hepatitis B virus (HBV)-inactivated polio vaccine (IPV)/Haemophilus influenza type b (Hib) at 2, 4, and 6 months, a booster dose of DTaP-HBV-IPV/Hib at 12 to 23 months induced strong anti-pertussis booster responses. Thus, neonatal aP priming did not lead to immune tolerance to pertussis antigens. However, it elicited bystander interference on HBV, Hib, and diphtheria responses. Copyright 2010 Mosby, Inc. All rights reserved.Entities:
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Year: 2010 PMID： 20303444 DOI： 10.1016/j.jpeds.2009.12.019
Source DB: PubMed Journal: J Pediatr ISSN： 0022-3476 Impact factor: 4.406