Literature DB >> 20303346

The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats: the effect of feeding S-adenosylmethionine.

F Bardag-Gorce1, J Li, J Oliva, S C Lu, B A French, S W French.   

Abstract

S-adenosylmethionine (SAMe), the major methyl donor for DNA and histone methylation was fed with ethanol for 1month in order to modify the effects of ethanol on rat liver. The following parameters were studied to determine the effects of SAMe; liver histology, the blood alcohol cycle (BAL), changes in gene expression mined from microarray analysis, changes in histone methylation, changes in liver SAMe levels and its metabolites and ADH. SAMe changed the type of fatty liver, reduced liver ALT levels and prevented the BAL cycle caused by intragastric ethanol feeding. Microarray analysis showed that SAMe feeding prevented most of the changes in gene expression induced by ethanol feeding, presumably by inducing H3K27me3 and gene silencing. H3K27me3 was significantly increased by SAMe with or without ethanol feeding. It is concluded that SAMe feeding stabilized global gene expression so that the changes in gene expression involved in the blood alcohol cycle were prevented. Copyright 2010 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20303346      PMCID： PMC2888598          DOI： 10.1016/j.yexmp.2010.03.004

Source DB:  PubMed          Journal:  Exp Mol Pathol        ISSN： 0014-4800            Impact factor:   3.362


  34 in total

Review 1.  Chromatin modulation by oncogenic transcription factors: new complexity, new therapeutic targets.

Authors:  Itsaso Hormaeche; Jonathan D Licht
Journal:  Cancer Cell       Date:  2007-06       Impact factor: 31.743

Review 2.  The pathogenesis and significance of the urinary alcohol cycle in rats fed ethanol intragastrically.

Authors:  Samuel W French
Journal:  Alcohol Clin Exp Res       Date:  2005-11       Impact factor: 3.455

3.  Differential effect of thioacetamide on hepatic methionine adenosyltransferase expression in the rat.

Authors:  Z Z Huang; J M Mato; G Kanel; S C Lu
Journal:  Hepatology       Date:  1999-05       Impact factor: 17.425

4.  The Polycomb group protein EZH2 directly controls DNA methylation.

Authors:  Emmanuelle Viré; Carmen Brenner; Rachel Deplus; Loïc Blanchon; Mario Fraga; Céline Didelot; Lluis Morey; Aleyde Van Eynde; David Bernard; Jean-Marie Vanderwinden; Mathieu Bollen; Manel Esteller; Luciano Di Croce; Yvan de Launoit; François Fuks
Journal:  Nature       Date:  2005-12-14       Impact factor: 49.962

Review 5.  S-Adenosylmethionine: a control switch that regulates liver function.

Authors:  Jose M Mato; Fernando J Corrales; Shelly C Lu; Matias A Avila
Journal:  FASEB J       Date:  2002-01       Impact factor: 5.191

6.  Gene expression modifications in the liver caused by binge drinking and S-adenosylmethionine feeding. The role of epigenetic changes.

Authors:  Jun Li; Fawzia Bardag-Gorce; Joan Oliva; Jennifer Dedes; Barbara A French; Samuel W French
Journal:  Genes Nutr       Date:  2009-12-04       Impact factor: 5.523

7.  Effects of S-adenosylmethionine on liver methionine metabolism and steatosis with ethanol-induced liver injury in rats.

Authors:  Zuojiong Gong; Shaonan Yan; Ping Zhang; Yanqing Huang; Luwen Wang
Journal:  Hepatol Int       Date:  2008-07-25       Impact factor: 6.047

8.  Catecholamines are involved in the mechanism of the urinary alcohol level cycle in rats fed ethanol intragastrically at a constant rate.

Authors:  Jun Li; Barbara A French; Paul Fu; Fawzia Bardag-Gorce; Samuel W French
Journal:  Life Sci       Date:  2004-11-05       Impact factor: 5.037

9.  Epigenetics of proteasome inhibition in the liver of rats fed ethanol chronically.

Authors:  Joan Oliva; Jennifer Dedes; Jun Li; Samuel-W French; Fawzia Bardag-Gorce
Journal:  World J Gastroenterol       Date:  2009-02-14       Impact factor: 5.742

10.  S-adenosyl-L-methionine attenuates oxidative stress and hepatic stellate cell activation in an ethanol-LPS-induced fibrotic rat model.

Authors:  Amel Karaa; Kyle J Thompson; Iain H McKillop; Mark G Clemens; Laura W Schrum
Journal:  Shock       Date:  2008-08       Impact factor: 3.454
View more
  10 in total

Review 1.  Histone modifications and alcohol-induced liver disease: are altered nutrients the missing link?

Authors:  Akshata Moghe; Swati Joshi-Barve; Smita Ghare; Leila Gobejishvili; Irina Kirpich; Craig J McClain; Shirish Barve
Journal:  World J Gastroenterol       Date:  2011-05-28       Impact factor: 5.742

2.  S-adenosylmethionine prevents the up regulation of Toll-like receptor (TLR) signaling caused by chronic ethanol feeding in rats.

Authors:  Joan Oliva; Fawzia Bardag-Gorce; Jun Li; Barbara A French; Samuel W French
Journal:  Exp Mol Pathol       Date:  2011-01-25       Impact factor: 3.362

3.  Proteasome inhibitor treatment reduced fatty acid, triacylglycerol and cholesterol synthesis.

Authors:  Joan Oliva; Samuel W French; Jun Li; Fawzia Bardag-Gorce
Journal:  Exp Mol Pathol       Date:  2012-03-16       Impact factor: 3.362

4.  Betaine feeding prevents the blood alcohol cycle in rats fed alcohol continuously for 1 month using the rat intragastric tube feeding model.

Authors:  J Li; X M Li; M Caudill; O Malysheva; F Bardag-Gorce; J Oliva; B A French; E Gorce; K Morgan; E Kathirvel; T Morgan; S W French
Journal:  Exp Mol Pathol       Date:  2011-06-25       Impact factor: 3.362

5.  S-adenosylmethionine decreases the peak blood alcohol levels 3 h after an acute bolus of ethanol by inducing alcohol metabolizing enzymes in the liver.

Authors:  Fawzia Bardag-Gorce; Joan Oliva; Wesley Wong; Stephanie Fong; Jun Li; Barbara A French; Samuel W French
Journal:  Exp Mol Pathol       Date:  2010-09-07       Impact factor: 3.362

6.  Epigenetic regulation of miR-34a expression in alcoholic liver injury.

Authors:  Fanyin Meng; Shannon S Glaser; Heather Francis; Fuquan Yang; Yuyan Han; Allison Stokes; Dustin Staloch; Jennifer McCarra; Jingang Liu; Julie Venter; Haiying Zhao; Xiuping Liu; Taylor Francis; Scott Swendsen; Chang-Gong Liu; Hidekazu Tsukamoto; Gianfranco Alpini
Journal:  Am J Pathol       Date:  2012-07-25       Impact factor: 4.307

Review 7.  The good, the bad, and the ugly with alcohol use and abuse on the heart.

Authors:  Robin K Walker; Valerie M Cousins; Nsini A Umoh; Miara A Jeffress; Delaram Taghipour; Mustafa Al-Rubaiee; Georges E Haddad
Journal:  Alcohol Clin Exp Res       Date:  2013-03-25       Impact factor: 3.455

8.  SAMe treatment prevents the ethanol-induced epigenetic alterations of genes in the Toll-like receptor pathway.

Authors:  Ronik Khachatoorian; David Dawson; Eden M Maloney; Julie Wang; Barbara A French; Samuel W French; Samuel W French
Journal:  Exp Mol Pathol       Date:  2012-10-06       Impact factor: 3.362

Review 9.  How to prevent alcoholic liver disease.

Authors:  S W French
Journal:  Exp Mol Pathol       Date:  2015-03-07       Impact factor: 3.362

10.  5-Aza-2'-deoxycytidine enhances lipopolysaccharide-induced inflammatory cytokine expression in human dental pulp cells by regulating TRAF6 methylation.

Authors:  Zhihui Feng; Minkang Zhan; Runsha Meng; Xinxuan Wang; Qiong Xu
Journal:  Bioengineered       Date:  2019-12       Impact factor: 3.269
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.