A Bayesian Maximum Entropy approach to address the change of support problem in the spatial analysis of childhood asthma prevalence across North Carolina.

The spatial analysis of data observed at different spatial observation scales leads to the change of support problem (COSP). A solution to the COSP widely used in linear spatial statistics consists in explicitly modeling the spatial autocorrelation of the variable observed at different spatial scales. We present a novel approach that takes advantage of the non-linear Bayesian Maximum Entropy (BME) extension of linear spatial statistics to address the COSP directly without relying on the classical linear approach. Our procedure consists in modeling data observed over large areas as soft data for the process at the local scale. We demonstrate the application of our approach to obtain spatially detailed maps of childhood asthma prevalence across North Carolina (NC). Because of the high prevalence of childhood asthma in NC, the small number problem is not an issue, so we can focus our attention solely to the COSP of integrating prevalence data observed at the county-level together with data observed at a targeted local scale equivalent to the scale of school-districts. Our spatially detailed maps can be used for different applications ranging from exploratory and hypothesis generating analyses to targeting intervention and exposure mitigation efforts.