| Literature DB >> 20299504 |
Seon Young Choi1,2, Je Hee Lee1,2, Yoon-Seong Jeon1,2, Hye Ri Lee2, Eun Jin Kim2, M Ansaruzzaman3, Nurul A Bhuiyan3, Hubert P Endtz3, S K Niyogi4, B L Sarkar4, G Balakrish Nair4, Binh Minh Nguyen5, Nguyen Tran Hien5, Cecil Czerkinsky2, John D Clemens2, Jongsik Chun1,2, Dong Wook Kim2.
Abstract
Atypical Vibrio cholerae O1 strains - hybrid strains (strains that cannot be classified either as El Tor or classical biotype) and altered strains (El Tor biotype strains that produce classical cholera toxin) - are currently prevalent in Asia and Africa. A total of 74 hybrid and altered strains that harboured classical cholera toxin were investigated by multilocus variable-number tandem repeat analysis (MLVA). The results showed that the hybrid/altered strains could be categorized into three groups and that they were distant from the El Tor strain responsible for the seventh cholera pandemic. Hybrid/altered strains with a tandem repeat of the classical CTX prophage on the small chromosome were divided into two MLVA groups (group I: Mozambique/Bangladesh group; group III: Vietnam group), and altered strains with the RS1-CTX prophage containing the El Tor type rstR and classical ctxB on the large chromosome were placed in two MLVA groups (group II: India/Bangladesh group; group III: India/Vietnam group).Entities:
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Year: 2010 PMID： 20299504 DOI： 10.1099/jmm.0.017939-0
Source DB: PubMed Journal: J Med Microbiol ISSN： 0022-2615 Impact factor: 2.472