Literature DB >> 20298

The in vitro metabolism of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane (o,p'-DDD) by dog adrenal mitochondria and metabolite covalent binding to mitochondrial macromolecules: a possible mechanism for the adrenocorticolytic effect.

F Martz, J A Straw.   

Abstract

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Year:  1977        PMID： 20298

Source DB:  PubMed          Journal:  Drug Metab Dispos        ISSN： 0090-9556            Impact factor:   3.922


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  8 in total

Review 1.  Current perspective in the diagnosis and treatment of adrenocortical carcinoma.

Authors:  D E Schteingart
Journal:  Rev Endocr Metab Disord       Date:  2001-08       Impact factor: 6.514

2.  Adrenocorticolytic DDT-metabolites: studies in mink, Mustela vison and otter, Lutra lutra.

Authors:  C J Jönsson; B O Lund; I Brandt
Journal:  Ecotoxicology       Date:  1993-03       Impact factor: 2.823

3.  The lack of antitumor effects of o,p'DDA excludes its role as an active metabolite of mitotane for adrenocortical carcinoma treatment.

Authors:  Ségolène Hescot; Angelo Paci; Atmane Seck; Abdelhamid Slama; Say Viengchareun; Séverine Trabado; Sylvie Brailly-Tabard; Abir Al Ghuzlan; Jacques Young; Eric Baudin; Marc Lombès
Journal:  Horm Cancer       Date:  2014-07-16       Impact factor: 3.869

Review 4.  Adrenocortical tumors and hyperplasias in childhood--etiology, genetics, clinical presentation and therapy.

Authors:  Jennifer A Sutter; Adda Grimberg
Journal:  Pediatr Endocrinol Rev       Date:  2006-09

5.  Effects of adrenolytic mitotane on drug elimination pathways assessed in vitro.

Authors:  Dirk Theile; Walter Emil Haefeli; Johanna Weiss
Journal:  Endocrine       Date:  2014-12-27       Impact factor: 3.633

Review 6.  Systemic therapy of Cushing's syndrome.

Authors:  Niels Eckstein; Bodo Haas; Moritz David Sebastian Hass; Vladlena Pfeifer
Journal:  Orphanet J Rare Dis       Date:  2014-08-05       Impact factor: 4.123

7.  Penetrance of the TP53 R337H Mutation and Pediatric Adrenocortical Carcinoma Incidence Associated with Environmental Influences in a 12-Year Observational Cohort in Southern Brazil.

Authors:  Tatiana E J Costa; Viviane K Q Gerber; Humberto C Ibañez; Viviane S Melanda; Ivy Z S Parise; Flora M Watanabe; Mara A D Pianovski; Carmem M C M Fiori; Ana L M R Fabro; Denise B da Silva; Diancarlos P Andrade; Heloisa Komechen; Monalisa C Mendes; Edna Carboni; Ana Paula Kuczynski; Emanuelle N Souza; Mariana M Paraizo; Marilea V C Ibañez; Laura M Castilho; Amanda F Cruz; Thuila F da Maia; Cleber Machado-Souza; Roberto Rosati; Claudia S Oliveira; Guilherme A Parise; Jaqueline D C Passos; José R S Barbosa; Mirna M O Figueiredo; Leniza Lima; Tiago Tormen; Cesar C Sabbaga; Sylvio G A Ávilla; Leila Grisa; Airton Aranha; Karina C F Tosin; Karin R P Ogradowski; Geneci Lima; Edith F Legal; Tania H Anegawa; Tânia L Mazzuco; André L Grion; José H G Balbinotti; Karin L Dammski; Rosiane G Melo; Nilton Kiesel Filho; Gislaine Custódio; Bonald C Figueiredo
Journal:  Cancers (Basel)       Date:  2019-11-16       Impact factor: 6.639

Review 8.  The Challenging Pharmacokinetics of Mitotane: An Old Drug in Need of New Packaging.

Authors:  Malik Salman Haider; Taufiq Ahmad; Jürgen Groll; Oliver Scherf-Clavel; Matthias Kroiss; Robert Luxenhofer
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2021-07-21       Impact factor: 2.441
  8 in total

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