Literature DB >> 20297806

One-step conversion of azine N-oxides to alpha-1,2,4-triazolo-, 1,2,3-triazolo, imidazolo-, and pyrazoloheteroarenes.

John M Keith1.   

Abstract

Pyridine, quinoline, isoquinoline, azaindole, and pyrimidine N-oxides were converted to their alpha-triazole and alpha-diazole derivatives by treatment with the corresponding p-toluenesulfonylazoles and Hunig's base at elevated temperatures.

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Year:  2010        PMID： 20297806     DOI： 10.1021/jo1001017

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  9 in total

1.  Construction of pyrazolo[3,4-b]pyridines and pyrazolo[4,3-c]pyridines by ring closure of 3-acylpyridine N-oxide tosylhydrazones.

Authors:  William J Lominac; Megan L D'Angelo; Mark D Smith; Darius A Ollison; James M Hanna
Journal:  Tetrahedron Lett       Date:  2012-02-22       Impact factor: 2.415

2.  Synthetic and mechanistic aspects of the regioselective base-mediated reaction of perfluoroalkyl- and perfluoroarylsilanes with heterocyclic N-oxides.

Authors:  David E Stephens; Gabriel Chavez; Martin Valdes; Monica Dovalina; Hadi D Arman; Oleg V Larionov
Journal:  Org Biomol Chem       Date:  2014-07-03       Impact factor: 3.876

3.  Core Replacements in a Potent Series of VEGFR-2 Inhibitors and Their Impact on Potency, Solubility, and hERG.

Authors:  Nello Mainolfi; James Powers; Erik Meredith; Jason Elliott; Karl G Gunderson; Stephen Poor; Fang Liu; Karen Anderson
Journal:  ACS Med Chem Lett       Date:  2016-03-16       Impact factor: 4.345

4.  Insights into the mechanistic and synthetic aspects of the Mo/P-catalyzed oxidation of N-heterocycles.

Authors:  Oleg V Larionov; David Stephens; Adelphe M Mfuh; Hadi D Arman; Anastasia S Naumova; Gabriel Chavez; Behije Skenderi
Journal:  Org Biomol Chem       Date:  2014-05-21       Impact factor: 3.876

5.  Uniting Amide Synthesis and Activation by PIII/PV-Catalyzed Serial Condensation: Three-Component Assembly of 2-Amidopyridines.

Authors:  Jeffrey M Lipshultz; Alexander T Radosevich
Journal:  J Am Chem Soc       Date:  2021-09-03       Impact factor: 16.383

6.  Palladium-Catalyzed C8-Selective C-H Arylation of Quinoline N-Oxides: Insights into the Electronic, Steric and Solvation Effects on the Site-Selectivity by Mechanistic and DFT Computational Studies.

Authors:  David E Stephens; Johant Lakey-Beitia; Abdurrahman C Atesin; Tülay A Ateşin; Gabriel Chavez; Hadi D Arman; Oleg V Larionov
Journal:  ACS Catal       Date:  2015-01-02       Impact factor: 13.084

7.  Catalytic Preparation of 1-Aryl-Substituted 1,2,4-Triazolium Salts.

Authors:  Scott M Hutchinson; Luis G Ardón-Muñoz; Margarita L Ratliff; Jeanne L Bolliger
Journal:  ACS Omega       Date:  2019-10-18

8.  Deoxygenative C2-heteroarylation of quinoline N-oxides: facile access to α-triazolylquinolines.

Authors:  Geetanjali S Sontakke; Rahul K Shukla; Chandra M R Volla
Journal:  Beilstein J Org Chem       Date:  2021-02-17       Impact factor: 2.883

9.  Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles.

Authors:  Qin Yang; Zhijian Yin; Lifang Zheng; Jianjun Yuan; Song Wei; Qiuping Ding; Yiyuan Peng
Journal:  RSC Adv       Date:  2019-02-18       Impact factor: 4.036
  9 in total

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