Literature DB >> 2028845

The association of age with aspirin esterase activity in human liver.

C Yelland1, J Summerbell, E Nicholson, B Herd, H Wynne, K W Woodhouse.   

Abstract

The activity of the phase 1 enzyme aspirin esterase was studied in liver tissue from 16 patients, aged 45-88 years. No correlation between age and enzyme activity was found in post-mitochondrial, cytosolic and microsomal fractions. These results provide further evidence that age is not a major determinant of the activity of hepatic drug-metabolizing enzymes in man.

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Year:  1991        PMID: 2028845     DOI: 10.1093/ageing/20.1.16

Source DB:  PubMed          Journal:  Age Ageing        ISSN: 0002-0729            Impact factor:   10.668


  8 in total

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Review 5.  A Narrative Review of Aspirin Resistance in VTE Prophylaxis for Orthopaedic Surgery.

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Review 6.  Age-related changes in hepatic function. Implications for drug therapy.

Authors:  K Woodhouse; H A Wynne
Journal:  Drugs Aging       Date:  1992 May-Jun       Impact factor: 3.923

Review 7.  Medication prescribing in frail older people.

Authors:  Ruth E Hubbard; M Sinead O'Mahony; Kenneth W Woodhouse
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8.  Plasma esterases and inflammation in ageing and frailty.

Authors:  Ruth E Hubbard; M Sinead O'Mahony; Brian L Calver; Ken W Woodhouse
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  8 in total

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