Literature DB >> 2027916

Serotonin, memory, and the aging brain.

W J McEntee1, T H Crook.   

Abstract

Serotonin is widely distributed throughout the central nervous system and is implicated in a variety of neural functions such as pain, feeding, sleep, sexual behavior, cardiac regulation and cognition. This paper is concerned with the last of these. Abnormalities of the serotonergic nervous system are well documented in pathologic studies of Alzheimer's disease and there is evidence suggesting that changes in this system occur in association with non-disease aging. Data on the role of serotonin in learning and memory and on the effects of aging on brain serotonin function are reviewed and discussed in relation to pharmacologic treatment strategies for the memory impairments associated with advancing age.

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Year:  1991        PMID： 2027916     DOI： 10.1007/bf02244194

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  72 in total

1.  Quantified regional and laminar distribution of the serotonin innervation in the anterior half of adult rat cerebral cortex.

Authors:  M A Audet; L Descarries; G Doucet
Journal:  J Chem Neuroanat       Date:  1989 Jan-Feb       Impact factor: 3.052

Review 2.  What is the nature of the role of the serotonergic nervous system in learning and memory: prospects for development of an effective treatment strategy for senile dementia.

Authors:  H J Altman; H J Normile
Journal:  Neurobiol Aging       Date:  1988 Sep-Dec       Impact factor: 4.673

3.  Evidence for a possible functional interaction between serotonergic and cholinergic mechanisms in memory retrieval.

Authors:  H J Altman; W S Stone; S O Ogren
Journal:  Behav Neural Biol       Date:  1987-07

Review 4.  Non-cholinergic neurotransmitter abnormalities in Alzheimer's disease.

Authors:  M Rossor; L L Iversen
Journal:  Br Med Bull       Date:  1986-01       Impact factor: 4.291

5.  Serotonin inhibits acetylcholine release from rat striatum slices: evidence for a presynaptic receptor-mediated effect.

Authors:  G Gillet; S Ammor; G Fillion
Journal:  J Neurochem       Date:  1985-12       Impact factor: 5.372

6.  Effect of p-chlorophenylalanine on avoidance learning of two differentially housed mouse strains.

Authors:  L Valzelli; L Pawłowski
Journal:  Neuropsychobiology       Date:  1979       Impact factor: 2.328

7.  5-Hydroxytryptamine-sensitive [3H]imipramine binding of protein nature in the human brain. II. Effect of normal aging and dementia disorders.

Authors:  J O Marcusson; I Alafuzoff; I T Bäckström; E Ericson; C G Gottfries; B Winblad
Journal:  Brain Res       Date:  1987-11-03       Impact factor: 3.252

8.  The effects of 8-hydroxy-2-(di-n-propylamino)tetralin and other serotonergic agonists on performance in a radial maze: a possible role for 5-HT1A receptors in memory.

Authors:  J C Winter; D T Petti
Journal:  Pharmacol Biochem Behav       Date:  1987-08       Impact factor: 3.533

9.  Manipulation of serotonin protects against an hypoxia-induced deficit of a passive avoidance response in rats.

Authors:  K F Strek; K R Spencer; V J DeNoble
Journal:  Pharmacol Biochem Behav       Date:  1989-05       Impact factor: 3.533

10.  Effect of quipazine, a serotonin-like drug, on striatal cholinergic interneurones.

Authors:  C Euvrard; F Javoy; A Herbet; J Glowinski
Journal:  Eur J Pharmacol       Date:  1977-02-07       Impact factor: 4.432
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  33 in total

1.  Age-Associated Memory Impairment.

Authors: 
Journal:  Curr Treat Options Neurol       Date:  2000-01       Impact factor: 3.598

2.  Age associated memory impairment.

Authors:  T H Crook; S H Ferris
Journal:  BMJ       Date:  1992-03-14

3.  Correlations among central serotonergic parameters and age-related emotional and cognitive changes assessed through the elevated T-maze and the Morris water maze.

Authors:  Luciana Oliveira; Frederico G Graeff; Silvia R C Pereira; Ieda F Oliveira-Silva; Glaura C Franco; Angela Maria Ribeiro
Journal:  Age (Dordr)       Date:  2010-01-13

4.  Intermolecular association provides specific optical and NMR signatures for serotonin at intravesicular concentrations.

Authors:  Suman Nag; J Balaji; P K Madhu; S Maiti
Journal:  Biophys J       Date:  2008-01-30       Impact factor: 4.033

5.  The impact of protein supplementation on cognitive performance in frail elderly.

Authors:  Nikita L van der Zwaluw; Ondine van de Rest; Michael Tieland; Jos J Adam; Gert Jan Hiddink; Luc J C van Loon; Lisette C P G M de Groot
Journal:  Eur J Nutr       Date:  2013-09-18       Impact factor: 5.614

6.  Effect of destruction of the 5-hydroxytryptaminergic pathways on the acquisition of temporal discrimination and memory for duration in a delayed conditional discrimination task.

Authors:  S S Al-Zahrani; M Y Ho; D N Martinez; M L Cabrera; C M Bradshaw; E Szabadi
Journal:  Psychopharmacology (Berl)       Date:  1996-01       Impact factor: 4.530

7.  Basal forebrain cholinergic immunolesion by 192IgG-saporin: evidence for a presynaptic location of subpopulations of alpha 2- and beta-adrenergic as well as 5-HT2A receptors on cortical cholinergic terminals.

Authors:  M Heider; R Schliebs; S Rossner; V Bigl
Journal:  Neurochem Res       Date:  1997-08       Impact factor: 3.996

8.  Chronic MDMA (ecstasy) use, cognition and mood.

Authors:  K McCardle; S Luebbers; J D Carter; R J Croft; C Stough
Journal:  Psychopharmacology (Berl)       Date:  2004-04-16       Impact factor: 4.530

9.  Differential effect of antipsychotics on place navigation of rats in the Morris water maze. A comparative study between novel and reference antipsychotics.

Authors:  T Skarsfeldt
Journal:  Psychopharmacology (Berl)       Date:  1996-03       Impact factor: 4.530

10.  Perturbed dentate gyrus function in serotonin 5-HT2C receptor mutant mice.

Authors:  L H Tecott; S F Logue; J M Wehner; J A Kauer
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205
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