Literature DB >> 2027536

Production of basic fibroblast growth factor in cultured rat brain microglia.

M Shimojo1, K Nakajima, N Takei, M Hamanoue, S Kohsaka.   

Abstract

The production of basic fibroblast growth factor (bFGF) in cultured rat brain microglia was investigated. Rat brain microglia were found to express mRNA of bFGF in analysis by polymerase chain reaction (PCR) technique. Basic FGF was also detected in microglial cell lysate by Western blot analysis. These results indicate that microglia produce bFGF and possibly contribute to the regulation of neuronal development and regeneration.

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Year:  1991        PMID: 2027536     DOI: 10.1016/0304-3940(91)90937-o

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  9 in total

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