Literature DB >> 202721

Oncogenicity of murine mammary tumor virus produced in tissue culture: brief communication.

L O Arthur, D L Fine, P Bentvelzen.   

Abstract

Murine mammary tumor virus (MuMTV), produced from a glucocorticoid-stimulated C3H mouse mammary adenocarcinoma cell line, was free of murine leukemia virus and oncogenic for weanling BALB/c mice. Adenocarcinomas were induced by MuMTV as early as 136 days post inoculation and with as low as 5 X 10(3) virus particles/mouse. Tumor incidence did not correlate directly with virus dose; rather, it was low at higher MuMTV concentrations (1.2 X 10(8) particles/mouse), reached and optimum at 1.3 X 10(5) particles/mouse, and decreased with virus dilution.

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Year:  1978        PMID： 202721     DOI： 10.1093/jnci/60.2.461

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  3 in total

1.  Establishment of a C3Hf mammary tumor cell line expressing endogenous mouse mammary tumor virus: antigenic and genetic relationships of this virus with highly oncogenic mouse mammary tumor viruses.

Authors:  L O Arthur; G G Lovinger; G Schochetman
Journal:  J Virol       Date:  1979-12       Impact factor: 5.103

2.  Immunological characterization of mouse mammary tumor virus p10 and its presence in mammary tumors and sera of tumor-bearing mice.

Authors:  L O Arthur; D L Fine
Journal:  J Virol       Date:  1979-04       Impact factor: 5.103

3.  The correlation between tissue differentiation and production of mammary tumor virus (MTV) in transplanted murine mammary tumors. Electron microscopic observations.

Authors:  C Schöpper; E Fasske; R Fetting; H Themann
Journal:  J Cancer Res Clin Oncol       Date:  1983       Impact factor: 4.553
  3 in total

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