Literature DB >> 2027127

Magnetic resonance imaging reflects the chemical changes of aging degeneration in the human intervertebral disk.

R H Pearce1, J P Thompson, G M Bebault, B Flak.   

Abstract

T2 weighed spin echo magnetic resonance images (MRI) of the intervertebral disks of 4 lumbar spines were graded and the nuclei pulposi were analyzed for water, collagen and proteoglycan. The brightness of the nuclear image correlated directly with the proteoglycan concentration, but not with the water or collagen. The dark midnuclear cleft had a collagen concentration slightly higher and a water concentration slightly lower than the adjacent zones; no corresponding differences in proteoglycan were seen, although the relationship with MRI grade was confirmed.

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Year:  1991        PMID： 2027127

Source DB:  PubMed          Journal:  J Rheumatol Suppl        ISSN： 0380-0903


  28 in total

1.  Degeneration of the cervical disc: histology compared with radiography and magnetic resonance imaging.

Authors:  A Christe; R Läubli; R Guzman; U Berlemann; R J Moore; G Schroth; P Vock; K O Lövblad
Journal:  Neuroradiology       Date:  2005-09-01       Impact factor: 2.804

2.  UTE MRI of the Osteochondral Junction.

Authors:  Won C Bae; Reni Biswas; Karen Chen; Eric Y Chang; Christine B Chung
Journal:  Curr Radiol Rep       Date:  2014-02-01

3.  Percutaneous discography: comparison of low-dose CT, fluoroscopy and MRI in the diagnosis of lumbar disc disruption.

Authors:  Claudia Kluner; Dietmar Kivelitz; Patrik Rogalla; Michael Putzier; Bernd Hamm; Christian Enzweiler
Journal:  Eur Spine J       Date:  2005-11-16       Impact factor: 3.134

4.  Intervertebral disc health preservation after six months of spinal growth modulation.

Authors:  Vidyadhar V Upasani; Christine L Farnsworth; Reid C Chambers; Tracey P Bastrom; Gregory M Williams; Robert L Sah; Koichi Masuda; Peter O Newton
Journal:  J Bone Joint Surg Am       Date:  2011-08-03       Impact factor: 5.284

5.  The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration.

Authors:  J Antoniou; T Steffen; F Nelson; N Winterbottom; A P Hollander; R A Poole; M Aebi; M Alini
Journal:  J Clin Invest       Date:  1996-08-15       Impact factor: 14.808

Review 6.  Quantitative magnetic resonance imaging of the lumbar intervertebral discs.

Authors:  Dosik Hwang; Sewon Kim; Nirusha A Abeydeera; Sheronda Statum; Koichi Masuda; Christine B Chung; Palanan Siriwanarangsun; Won C Bae
Journal:  Quant Imaging Med Surg       Date:  2016-12

7.  Assessment of lumbar disc herniaton using fractional anisotropy in diffusion tensor imaging along with conventional T2-weighted imaging.

Authors:  Marco Perri; Marialuisa D'Elia; Giulia Castorani; Rosario Francesco Balzano; Annamaria Pennelli; Bilal Al-Badayneh; Annunziata Russo; Giuseppe Guglielmi; Teresa Popolizio
Journal:  Neuroradiol J       Date:  2019-11-27

Review 8.  Clinical diagnosis for discogenic low back pain.

Authors:  Yin-gang Zhang; Tuan-mao Guo; Xiong Guo; Shi-xun Wu
Journal:  Int J Biol Sci       Date:  2009-10-13       Impact factor: 6.580

9.  Therapeutic effects of adenovirus-mediated growth and differentiation factor-5 in a mice disc degeneration model induced by annulus needle puncture.

Authors:  Haixiang Liang; Shen-Ying Ma; Gang Feng; Francis H Shen; Xudong Joshua Li
Journal:  Spine J       Date:  2009-11-18       Impact factor: 4.166

10.  Magnetic resonance imaging-based interpretation of degenerative changes in the lower lumbar segments and therapeutic consequences.

Authors:  Adel Maataoui; Thomas J Vogl; M Fawad Khan
Journal:  World J Radiol       Date:  2015-08-28
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