Demonstration of CT hyperdensity in patients with acute renal failure associated with rhabdomyolysis.

Abnormal hyperdensity consistent with skeletal muscle calcification was shown by CT in four of eight (50%) patients with rhabdomyolysis. This finding correlated significantly with antecedent hypocalcemia (p = 0.01) and renal insufficiency (p = 0.03). In patients with rhabdomyolysis, CT can show abnormal skeletal muscle hyperdensity consistent with calcification. A work-up for hypocalcemia and renal insufficiency should be initiated when this finding is demonstrated. Noncontrast CT could be useful in cases of acute renal failure of unknown etiology to help diagnose occult rhabdomyolysis.