| Literature DB >> 2026726 |
A Longo1, M Di Toro, C Galimberti, A Carenzi.
Abstract
An automatic mass spectrometric method for the quantitation of N-acetylcysteine (NAC) in human plasma has been developed. NAC was extracted from plasma with ethyl acetate and derivatized in two steps with 2-propanol and pentafluoropropionic anhydride. The volatile derivative obtained was ideal for gas chromatographic-mass spectrometric analysis. Data obtained by analysing the plasma of healthy volunteers to whom 600 mg of NAC had been orally given are reported.Entities:
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Year: 1991 PMID： 2026726 DOI： 10.1016/0378-4347(91)80614-i
Source DB: PubMed Journal: J Chromatogr