Literature DB >> 2025641

Sequence comparison of the sodium-D-glucose cotransport systems in rabbit renal and intestinal epithelia.

A I Morrison1, M Panayotova-Heiermann, G Feigl, B Schölermann, R K Kinne.   

Abstract

Using an isolated 1.2 kbp PCR product as specific probe, the rabbit renal cortex sodium-D-glucose cotransport system has been found and cloned from a renal cortex cDNA library. Two overlapping cDNA clones were found, one with a length of 2.1 kbp and one of 1.1 kbp resulting in a total sequence of 2.2 kbp without the poly(A) tail. Northern blot hybridization indicated a transcript of approx. 2.4 kb in size. Tissue distribution in the rabbit kidney and intestine indicates that this sequence is present in renal cortex, renal medulla and small intestine in different proportions. It is proposed that this clone codes for a member of the sodium-D-glucose cotransporter systems.

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Year:  1991        PMID： 2025641     DOI： 10.1016/0167-4781(91)90093-2

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  11 in total

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Authors:  C Chenu; A Berteloot
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5.  A deletion polymorphism in the human alpha-2-macroglobulin (A2M) gene.

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10.  Molecular characterization and nutritional regulation of sodium-dependent glucose cotransporter 1 (Sglt1) in blunt snout bream (Megalobrama amblycephala).

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