Literature DB >> 20234757

Medicinal properties of fractionated acetone/water neem [Azadirachta indica] leaf extract from Nigeria: a review.

Ugochukwu B Anyaehie1.   

Abstract

The global scenario is now supporting the development of modern drugs from less toxic plant products with proven medicinal properties. Each part of neem plant [Azadirachta indica A. Juss] reportedly have various medicinal properties and has been in use in many continents for centuries. Recently, a fractionated neem-leaf extract known as IRAB with reported activities against Malaria, HIV/AIDS and cancer has been developed into a drug and currently marketed in Nigeria as IRACAP. This paper reviews the medicinal properties, clinical studies and safety concerns of this fractionated acetone-water neem leaves extract as a footstep to further studies both on the extract and/or its chemical constituents.

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Year:  2009        PMID： 20234757     DOI： 10.4314/njps.v24i2.52926

Source DB:  PubMed          Journal:  Niger J Physiol Sci        ISSN： 0794-859X


  10 in total

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Journal:  Clin Cancer Res       Date:  2013-10-29       Impact factor: 12.531

2.  Preclinical evaluation of the supercritical extract of azadirachta indica (neem) leaves in vitro and in vivo on inhibition of prostate cancer tumor growth.

Authors:  Qiang Wu; Manish Kohli; H Robert Bergen; John C Cheville; R Jeffrey Karnes; Hong Cao; Charles Y F Young; Donald J Tindall; Mark A McNiven; Krishna Vanaja Donkena
Journal:  Mol Cancer Ther       Date:  2014-03-27       Impact factor: 6.261

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Authors:  Venugopalan Santhosh Kumar; Visweswaran Navaratnam
Journal:  Asian Pac J Trop Biomed       Date:  2013-07

4.  Protective effect of Azadirachta indica extract against Eimeria papillata-induced coccidiosis.

Authors:  Mohamed A Dkhil; Saleh Al-Quraishy; Ahmed E Abdel Moneim; Denis Delic
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5.  Novel molecular targets of Azadirachta indica associated with inhibition of tumor growth in prostate cancer.

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6.  Antiangiogenic Effects and Therapeutic Targets of Azadirachta indica Leaf Extract in Endothelial Cells.

Authors:  Saswati Mahapatra; Charles Y F Young; Manish Kohli; R Jeffrey Karnes; Eric W Klee; Michael W Holmes; Donald J Tindall; Krishna Vanaja Donkena
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7.  Impact of repeated NeemAzal-treated blood meals on the fitness of Anopheles stephensi mosquitoes.

Authors:  Edson G Dembo; Solomon M Abay; Nisha Dahiya; Johnbull S Ogboi; George K Christophides; Giulio Lupidi; Giuseppina Chianese; Leonardo Lucantoni; Annette Habluetzel
Journal:  Parasit Vectors       Date:  2015-02-10       Impact factor: 3.876

8.  Effects of Azadirachta indica seed kernel extracts on early erythrocytic schizogony of Plasmodium berghei and pro-inflammatory response in inbred mice.

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Journal:  Malar J       Date:  2019-02-08       Impact factor: 2.979

9.  Effect of Azadirachta indica and Senna siamea Decoction on CD4+ and CD8+ Level, Toxicological, and Antioxidant Profile in HIV/AIDS Positive Persons.

Authors:  Oumarou Goni Hamadama; Mbah Ntepe Leonel Javeres; Nyunaï Nyemb; Medou Mba Fabrice; Pettang Tomen Manuela Elsa
Journal:  J Toxicol       Date:  2021-06-23

Review 10.  The HMOX1 Pathway as a Promising Target for the Treatment and Prevention of SARS-CoV-2 of 2019 (COVID-19).

Authors:  Neelu Batra; Cristabelle De Souza; Jyoti Batra; Alan G Raetz; Ai-Ming Yu
Journal:  Int J Mol Sci       Date:  2020-09-03       Impact factor: 5.923
  10 in total

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