OBJECTIVE: This is a guideline review of the application of diagnostic tests and diagnostic accuracy in surgical research. SUMMARY BACKGROUND DATA: There is an increasing use of diagnostic tests in surgery, and an understanding of the accuracy for each test is important for surgeons. METHODS: This methodological review outlines the basic concepts of diagnostic test accuracy, including sensitivity, specificity, diagnostic odds ratio, likelihood ratios, and predictive values. Sources of bias in diagnostic accuracy studies are explained in simplified terms. The graphical methods used to present diagnostic accuracy are demonstrated. Study quality issues are outlined using published guidelines. Finally, the principles of diagnostic meta-analysis, including more advanced approaches such as bivariate and hierarchical summary receiver operating characteristic methods are explained. CONCLUSION: In the era of evidence-based surgery, the ability to understand and interpret the fundamental principles of diagnostic accuracy literature is vital to improve patient care and reduce the confusion in clinical practice over the most appropriate diagnostic test.
OBJECTIVE: This is a guideline review of the application of diagnostic tests and diagnostic accuracy in surgical research. SUMMARY BACKGROUND DATA: There is an increasing use of diagnostic tests in surgery, and an understanding of the accuracy for each test is important for surgeons. METHODS: This methodological review outlines the basic concepts of diagnostic test accuracy, including sensitivity, specificity, diagnostic odds ratio, likelihood ratios, and predictive values. Sources of bias in diagnostic accuracy studies are explained in simplified terms. The graphical methods used to present diagnostic accuracy are demonstrated. Study quality issues are outlined using published guidelines. Finally, the principles of diagnostic meta-analysis, including more advanced approaches such as bivariate and hierarchical summary receiver operating characteristic methods are explained. CONCLUSION: In the era of evidence-based surgery, the ability to understand and interpret the fundamental principles of diagnostic accuracy literature is vital to improve patient care and reduce the confusion in clinical practice over the most appropriate diagnostic test.
Authors: Ravi Aggarwal; Viknesh Sounderajah; Guy Martin; Daniel S W Ting; Alan Karthikesalingam; Dominic King; Hutan Ashrafian; Ara Darzi Journal: NPJ Digit Med Date: 2021-04-07
Authors: Olivier Courage; Louise Strom; Floris van Rooij; Matthieu Lalevée; Donatien Heuzé; Pierre Emanuel Papin; Michael Butnaru; Jacobus Hendrik Müller Journal: EFORT Open Rev Date: 2021-11-19
Authors: Carol C Cheung; Penny Barnes; Gilbert Bigras; Scott Boerner; Jagdish Butany; Fiorella Calabrese; Christian Couture; Jean Deschenes; Hala El-Zimaity; Gabor Fischer; Pierre O Fiset; John Garratt; Laurette Geldenhuys; C Blake Gilks; Marius Ilie; Diana Ionescu; Hyun J Lim; Lisa Manning; Adnan Mansoor; Robert Riddell; Catherine Ross; Sinchita Roy-Chowdhuri; Alan Spatz; Paul E Swanson; Victor A Tron; Ming-Sound Tsao; Hangjun Wang; Zhaolin Xu; Emina E Torlakovic Journal: Appl Immunohistochem Mol Morphol Date: 2019 Nov/Dec
Authors: Emina Torlakovic; Hyun J Lim; Julien Adam; Penny Barnes; Gilbert Bigras; Anthony W H Chan; Carol C Cheung; Jin-Haeng Chung; Christian Couture; Pierre O Fiset; Daichi Fujimoto; Gang Han; Fred R Hirsch; Marius Ilie; Diana Ionescu; Chao Li; Enrico Munari; Katsuhiro Okuda; Marianne J Ratcliffe; David L Rimm; Catherine Ross; Rasmus Røge; Andreas H Scheel; Ross A Soo; Paul E Swanson; Maria Tretiakova; Ka F To; Gilad W Vainer; Hangjun Wang; Zhaolin Xu; Dirk Zielinski; Ming-Sound Tsao Journal: Mod Pathol Date: 2019-08-05 Impact factor: 7.842