Literature DB >> 20232337

A new long-chain alkene and antituberculosis constituents from the leaves of Pourthiaea lucida.

Jih-Jung Chen1, Wen-Jiou Lin, Po-Chuen Shieh, Ih-Sheng Chen, Chien-Fang Peng, Ping-Jyun Sung.   

Abstract

A new long-chain alkene, dotriacont-1-ene (1), was isolated from the leaves of Pourthiaea lucida, together with twelve known compounds. The structure of this new compound was determined by NMR and mass-spectrometric analyses. Among the isolated compounds, alpha-tocospiro A (2), alpha-tocopheryl quinone (4), and (E)-phytol (5) exhibited antituberculosis activities (MICs <or=30 microg/ml) against Mycobacterium tuberculosis H(37)Rv in vitro.

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Year:  2010        PMID： 20232337     DOI： 10.1002/cbdv.200900198

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN： 1612-1872            Impact factor:   2.408


  3 in total

1.  Identification of plant-derived natural products as potential inhibitors of the Mycobacterium tuberculosis proteasome.

Authors:  Yuejuan Zheng; Xin Jiang; Feng Gao; Junxiang Song; Jinxia Sun; Lixin Wang; Xiaoxia Sun; Zhenhui Lu; Huiyong Zhang
Journal:  BMC Complement Altern Med       Date:  2014-10-15       Impact factor: 3.659

2.  Evaluating the anti Mycobacterium tuberculosis activity of Alpinia galanga (L.) Willd. axenically under reducing oxygen conditions and in intracellular assays.

Authors:  Pooja Gupta; Purva Bhatter; Desiree D'souza; Monica Tolani; Poonam Daswani; Pundarikakshudu Tetali; Tannaz Birdi
Journal:  BMC Complement Altern Med       Date:  2014-03-04       Impact factor: 3.659

3.  Synthesis, LC-MS/MS analysis, and biological evaluation of two vaccine candidates against ticks based on the antigenic P0 peptide from R. sanguineus linked to the p64K carrier protein from Neisseria meningitidis.

Authors:  Luis Javier González; Pedro E Encinosa Guzmán; Wendy Machado; Satomy Pousa; Alejandro Leyva; Ana Laura Cano Arguelles; Gleysin Cabrera; Luis Ariel Espinosa; Rubén Parra; Rachel Hernández; Yamil Bello Soto; Frank L Ledesma; Marisdania Joglar; Osmany Guirola; Louise Ulrich Kurt; Paulo C Carvalho; Ania Cabrales; Hilda Garay; Vladimir Besada; Rosario Durán; Toshifumi Takao; Mario Pablo Estrada; Alina Rodríguez-Mallon
Journal:  Anal Bioanal Chem       Date:  2021-08-03       Impact factor: 4.478
  3 in total

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