BACKGROUND: Periprosthetic capsules are a common reaction of the body to silicone or polyurethane breast implants. The aim of this study was to evaluate similarities and differences in the histological features of periprosthetic capsules surrounding silicone implants and polyurethane foam-coated implants and to correlate those features with the age of the implants. METHODS: Tissues were studied from 41 periprosthetic capsules surrounding textured prostheses and from 20 capsules surrounding polyurethane foam-coated implants. For each sample we evaluated synovial metaplasia, density of collagen fibers or fibrosis, orientation of collagen fibers, and foreign body reaction (granulomatous reaction). RESULTS: Synovial metaplasia was seen in the capsular tissue from both types of implant, but more so from capsules surrounding polyurethane implants more than 5 years old. The density and orientation of the collagen fibers and the foreign body reaction were very similar for the two types of implant.
BACKGROUND: Periprosthetic capsules are a common reaction of the body to silicone or polyurethane breast implants. The aim of this study was to evaluate similarities and differences in the histological features of periprosthetic capsules surrounding silicone implants and polyurethane foam-coated implants and to correlate those features with the age of the implants. METHODS: Tissues were studied from 41 periprosthetic capsules surrounding textured prostheses and from 20 capsules surrounding polyurethane foam-coated implants. For each sample we evaluated synovial metaplasia, density of collagen fibers or fibrosis, orientation of collagen fibers, and foreign body reaction (granulomatous reaction). RESULTS: Synovial metaplasia was seen in the capsular tissue from both types of implant, but more so from capsules surrounding polyurethane implants more than 5 years old. The density and orientation of the collagen fibers and the foreign body reaction were very similar for the two types of implant.
Authors: Margaux Pontailler; Eranka Illangakoon; Gareth R Williams; Camille Marijon; Valérie Bellamy; Daniel Balvay; Gwenhael Autret; Valérie Vanneaux; Jérôme Larghero; Valérie Planat-Benard; Marie-Cécile Perier; Patrick Bruneval; Philippe Menasché; David Kalfa Journal: Tissue Eng Part A Date: 2015-03-12 Impact factor: 3.845
Authors: Janine M Bui; TracyAnn Perry; Cindy D Ren; Barbara Nofrey; Steven Teitelbaum; Dennis E Van Epps Journal: Aesthetic Plast Surg Date: 2015-03-06 Impact factor: 2.326
Authors: Andreas Larsen; Louise E Rasmussen; Leonia F Rasmussen; Tim K Weltz; Mathilde N Hemmingsen; Steen S Poulsen; Jens C B Jacobsen; Peter Vester-Glowinski; Mikkel Herly Journal: Aesthetic Plast Surg Date: 2021-07-26 Impact factor: 2.326
Authors: Patrina S P Poh; Verena Schmauss; Jacqui A McGovern; Daniel Schmauss; Mohit P Chhaya; Peter Foehr; Markus Seeger; Vasilis Ntziachristos; Dietmar W Hutmacher; Martijn van Griensven; Jan-Thorsten Schantz; Elizabeth R Balmayor Journal: Eur J Med Res Date: 2018-06-04 Impact factor: 2.175