Literature DB >> 20229015

How conformational transition depends on hydrophobicity of elastin-like polypeptides.

H Arkin1, M Bilsel.   

Abstract

The three-dimensional structures of elastin-like polypeptides Val1-Pro2-Gly3-Xaa4-Gly5 were investigated by using the multicanonical Monte Carlo (MC) simulation procedure. By substituting different amino acids in the fourth position of the sequence, the thermodynamical variables are calculated in vacuo and in solvent to determine the hydrophobicity dependence of the conformational transition temperatures of the peptides. Resultant hydrophobicity scale is in good agreement with many hydrophobicity scales.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20229015     DOI： 10.1140/epje/i2010-10573-7

Source DB:  PubMed          Journal:  Eur Phys J E Soft Matter        ISSN： 1292-8941            Impact factor:   1.890


  15 in total

1.  Folding of a small helical protein using hydrogen bonds and hydrophobicity forces.

Authors:  Giorgio Favrin; Anders Irbäck; Stefan Wallin
Journal:  Proteins       Date:  2002-05-01

2.  An atomically detailed study of the folding pathways of protein A with the stochastic difference equation.

Authors:  Avijit Ghosh; Ron Elber; Harold A Scheraga
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-24       Impact factor: 11.205

3.  Metropolis simulations of Met-Enkephalin with solvent-accessible area parametrizations.

Authors:  Bernd A Berg; Hsiao-Ping Hsu
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2004-02-27

4.  New Monte Carlo technique for studying phase transitions.

Authors: 
Journal:  Phys Rev Lett       Date:  1988-12-05       Impact factor: 9.161

5.  Characterization of protein-folding pathways by reduced-space modeling.

Authors:  Sebastian Kmiecik; Andrzej Kolinski
Journal:  Proc Natl Acad Sci U S A       Date:  2007-07-16       Impact factor: 11.205

6.  Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia.

Authors:  D E Meyer; G A Kong; M W Dewhirst; M R Zalutsky; A Chilkoti
Journal:  Cancer Res       Date:  2001-02-15       Impact factor: 12.701

7.  Comparison of atomic solvation parametric sets: applicability and limitations in protein folding and binding.

Authors:  A H Juffer; F Eisenhaber; S J Hubbard; D Walther; P Argos
Journal:  Protein Sci       Date:  1995-12       Impact factor: 6.725

Review 8.  Conformations of the repeat peptides of elastin in solution: an application of proton and carbon-13 magnetic resonance to the determination of polypeptide secondary structure.

Authors:  D W Urry; M M Long
Journal:  CRC Crit Rev Biochem       Date:  1976-06

9.  Synthetic fragments and analogues of elastin. II. Conformational studies.

Authors:  A M Tamburro; V Guantieri; L Pandolfo; A Scopa
Journal:  Biopolymers       Date:  1990 Mar-Apr       Impact factor: 2.505

10.  Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy.

Authors:  Matthew R Dreher; Drazen Raucher; Narayanan Balu; O Michael Colvin; Susan M Ludeman; Ashutosh Chilkoti
Journal:  J Control Release       Date:  2003-08-28       Impact factor: 9.776
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.