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Literature DB >> 20226717

Directing systemic oncolytic viral delivery to tumors via carrier cells.

Hiroshi Nakashima¹, Balveen Kaur, E A Chiocca.

Abstract

The systemic administration of oncolytic virus (OV) is often inefficient due to clearance of the virus by host defense mechanism and spurious targeting of non-cancer tissues through the bloodstream. Cell mediated OV delivery could hide the virus from host defenses and direct them toward tumors: Mesenchymal and neural stem cells have been described to possess tumor-homing ability as well as the capacity to deliver OVs. In this review, we will focus on approaches where OV and carrier cells are utilized for cancer therapy. Effective cellular internalization and replication of OVs need to occur both in cancer and carrier cells. We thus will discuss the current challenges faced by the use of OV delivery via carrier cells. 2010 Elsevier Ltd. All rights reserved.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2010 PMID： 20226717 PMCID： PMC3109423 DOI： 10.1016/j.cytogfr.2010.02.004

Source DB: PubMed Journal: Cytokine Growth Factor Rev ISSN： 1359-6101 Impact factor: 7.638

70 in total

1. A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

Authors: J Fueyo; C Gomez-Manzano; R Alemany; P S Lee; T J McDonnell; P Mitlianga; Y X Shi; V A Levin; W K Yung; A P Kyritsis
Journal: Oncogene Date: 2000-01-06 Impact factor: 9.867

Review 2. Mammalian neural stem cells.

Authors: F H Gage
Journal: Science Date: 2000-02-25 Impact factor: 47.728

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Journal: Nat Med Date: 2000-04 Impact factor: 53.440

4. Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms.

Authors: N G Rainov; C Zimmer; M Chase; C M Kramm; E A Chiocca; R Weissleder; X O Breakefield
Journal: Hum Gene Ther Date: 1995-12 Impact factor: 5.695

5. Adipose-derived stem cells as therapeutic delivery vehicles of an oncolytic virus for glioblastoma.

Authors: Darnell T Josiah; Dongqin Zhu; Fernanda Dreher; John Olson; Grant McFadden; Hannah Caldas
Journal: Mol Ther Date: 2009-11-10 Impact factor: 11.454

6. Gene transfer to cervical cancer with fiber-modified adenoviruses.

Authors: Daniel T Rein; Martina Breidenbach; Hongju Wu; Tie Han; Yosef S Haviv; Minghui Wang; Tyler O Kirby; Yosuke Kawakami; Peter Dall; Ronald D Alvarez; David T Curiel
Journal: Int J Cancer Date: 2004-09-20 Impact factor: 7.396

7. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas.

Authors: T Mineta; S D Rabkin; T Yazaki; W D Hunter; R L Martuza
Journal: Nat Med Date: 1995-09 Impact factor: 53.440

8. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors.

Authors: K W Culver; Z Ram; S Wallbridge; H Ishii; E H Oldfield; R M Blaese
Journal: Science Date: 1992-06-12 Impact factor: 47.728

9. Ischemia-induced neurogenesis of neocortical layer 1 progenitor cells.

Authors: Koji Ohira; Takahiro Furuta; Hiroyuki Hioki; Kouichi C Nakamura; Eriko Kuramoto; Yasuyo Tanaka; Nobuo Funatsu; Keiko Shimizu; Takao Oishi; Motoharu Hayashi; Tsuyoshi Miyakawa; Takeshi Kaneko; Shun Nakamura
Journal: Nat Neurosci Date: 2009-12-27 Impact factor: 24.884

10. Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies.

Authors: Richard T Frank; Marissa Edmiston; Stephen E Kendall; Joseph Najbauer; Chia-Wei Cheung; Thewodros Kassa; Marianne Z Metz; Seung U Kim; Carlotta A Glackin; Anna M Wu; Paul J Yazaki; Karen S Aboody
Journal: PLoS One Date: 2009-12-15 Impact factor: 3.240

38 in total

Review 9. Gene Delivery in Neuro-Oncology.

Authors: Karan Dixit; Priya Kumthekar
Journal: Curr Oncol Rep Date: 2017-09-02 Impact factor: 5.075

10. Current status of gene therapy for brain tumors.

Authors: Andrea M Murphy; Samuel D Rabkin
Journal: Transl Res Date: 2012-12-11 Impact factor: 7.012

Directing systemic oncolytic viral delivery to tumors via carrier cells.

1. A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

Review 2. Mammalian neural stem cells.

3. Gene therapy of experimental brain tumors using neural progenitor cells.

4. Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms.

5. Adipose-derived stem cells as therapeutic delivery vehicles of an oncolytic virus for glioblastoma.

6. Gene transfer to cervical cancer with fiber-modified adenoviruses.

7. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas.

8. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors.

9. Ischemia-induced neurogenesis of neocortical layer 1 progenitor cells.

10. Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies.

Review 1. Stem cells as therapeutic vehicles for the treatment of high-grade gliomas.

2. An intravenous stimulus package for oncolytic virotherapy.

Review 3. Engineering antiphagocytic biomimetic drug carriers.

Review 4. Thunder and lightning: immunotherapy and oncolytic viruses collide.

Review 5. Engineering Stem Cells for Biomedical Applications.

Review 6. Oncolytic viruses and their application to cancer immunotherapy.

Review 7. Changing faces in virology: the dutch shift from oncogenic to oncolytic viruses.

Review 8. Vesicular stomatitis virus as a flexible platform for oncolytic virotherapy against cancer.

Review 9. Gene Delivery in Neuro-Oncology.

10. Current status of gene therapy for brain tumors.