Literature DB >> 20225243

Cucurbitane-type triterpene glycosides from the fruits of Momordica charantia.

Xuan Nhiem Nguyen1, Van Kiem Phan, Van Minh Chau, Khac Ban Ninh, Xuan Cuong Nguyen, Minh Ha Le, Huu Tai Bui, Hong Quang Tran, Huu Tung Nguyen, Young Ho Kim.   

Abstract

The chemical study of Momordica charantia fruits led to the isolation of three new cucurbitane triterpene glycosides, momordicosides U, V, and W (1-3). The structures of these compounds were determined to be (19R, 23R)-5beta, 19-epoxy-19-methoxycucurbita-6,24-diene-3beta, 23-diol 3-O-beta-D-allopyranoside (1), (23R)-5beta, 19-epoxycucurbita-6,24-diene-3beta, 23-diol 3-O-beta-D-allopyranoside (2), and (19R)-5beta, 19-epoxy-19,25-dihydroxycucurbita-6,23(E)-diene-3beta-ol 3-O-beta-D-glucopyranoside (3), by chemical and spectroscopic methods. Copyright 2010 John Wiley & Sons, Ltd.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20225243     DOI: 10.1002/mrc.2582

Source DB:  PubMed          Journal:  Magn Reson Chem        ISSN: 0749-1581            Impact factor:   2.447


  7 in total

Review 1.  Bitter melon: a panacea for inflammation and cancer.

Authors:  Prasad R Dandawate; Dharmalingam Subramaniam; Subhash B Padhye; Shrikant Anant
Journal:  Chin J Nat Med       Date:  2016-02

2.  Inhibition of nuclear transcription factor-κB and activation of peroxisome proliferator-activated receptors in HepG2 cells by cucurbitane-type triterpene glycosides from Momordica charantia.

Authors:  Nguyen Xuan Nhiem; Pham Hai Yen; Nguyen Thi Thanh Ngan; Tran Hong Quang; Phan Van Kiem; Chau Van Minh; Bui Huu Tai; Nguyen Xuan Cuong; Seok Bean Song; Young Ho Kim
Journal:  J Med Food       Date:  2012-01-16       Impact factor: 2.786

3.  13, 14-Epoxyoleanan-3-ol-acetate: A Male Fertility-Enhancing Constituent from Hexane Fraction of Momordica charantia L. (Cucurbitaceae).

Authors:  Oluwasegun Adedokun; Adebayo Gbolade; Bunyaminu Ayinde
Journal:  Turk J Pharm Sci       Date:  2022-04-29

Review 4.  Promise of bitter melon (Momordica charantia) bioactives in cancer prevention and therapy.

Authors:  Komal Raina; Dileep Kumar; Rajesh Agarwal
Journal:  Semin Cancer Biol       Date:  2016-07-21       Impact factor: 15.707

Review 5.  Beneficial role of bitter melon supplementation in obesity and related complications in metabolic syndrome.

Authors:  Md Ashraful Alam; Riaz Uddin; Nusrat Subhan; Md Mahbubur Rahman; Preeti Jain; Hasan Mahmud Reza
Journal:  J Lipids       Date:  2015-01-12

6.  α-Glucosidase Inhibitory Activity of Cycloartane-Type Triterpenes Isolated from Indonesian Stingless Bee Propolis and Their Structure-Activity Relationship.

Authors:  Niken Pujirahayu; Debu Kumar Bhattacharjya; Toshisada Suzuki; Takeshi Katayama
Journal:  Pharmaceuticals (Basel)       Date:  2019-07-01

7.  Anti-Inflammatory, Antidiabetic Properties and In Silico Modeling of Cucurbitane-Type Triterpene Glycosides from Fruits of an Indian Cultivar of Momordica charantia L.

Authors:  Wilmer H Perera; Siddanagouda R Shivanagoudra; Jose L Pérez; Da Mi Kim; Yuxiang Sun; Guddadarangavvanahally K Jayaprakasha; Bhimanagouda S Patil
Journal:  Molecules       Date:  2021-02-16       Impact factor: 4.411

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.