Literature DB >> 20224716

A case of lumbar metastasis of choriocarcinoma masquerading as an extraosseous extension of vertebral hemangioma.

Ji Hoon Lee1, Chan Woo Park, Dong Hae Chung, Woo Kyung Kim.   

Abstract

We report here on an uncommon case of metastatic choriocarcinoma to the lung, brain and lumbar spine. A 33-year-old woman was admitted to the pulmonary department with headache, dyspnea and hemoptysis. There was a history of cesarean section due to intrauterine fetal death at 37-weeks gestation and this occurred 2 weeks before admission to the pulmonary department. The radiological studies revealed a nodular lung mass with hypervascularity in the left upper lobe and also a brain parenchymal lesion in the parietal lobe with marginal bleeding and surrounding edema. She underwent embolization for the lung lesion, which was suspected to be an arteriovenous malformation according to the pulmonary arteriogram. Approximately 10 days after discharge from the pulmonary department, she was readmitted due to back pain and progressive paraparesis. The neuroradiological studies revealed a hypervascular tumor occupying the entire L3 vertebral body and pedicle, and the tumor extended to the epidural area. She underwent embolization of the hypervascular lesion of the lumbar spine, and after which injection of polymethylmethacrylate in the L3 vertebral body, total laminectomy of L3, subtotal removal of the epidural mass and screw fixation of L2 and L4 were performed. The result of biopsy was a choriocarcinoma.

Entities:  

Keywords:  Metastatic choriocarconoma; Spinal metastasis

Year:  2010        PMID: 20224716      PMCID: PMC2836452          DOI: 10.3340/jkns.2010.47.2.143

Source DB:  PubMed          Journal:  J Korean Neurosurg Soc        ISSN: 1225-8245


  21 in total

1.  Gestational trophoblastic diseases: 3. Human chorionic gonadotropin-free beta-subunit, a reliable marker of placental site trophoblastic tumors.

Authors:  Laurence A Cole; Sarah A Khanlian; Carolyn Y Muller; Almareena Giddings; Ernest Kohorn; Ross Berkowitz
Journal:  Gynecol Oncol       Date:  2006-05-02       Impact factor: 5.482

2.  Lumbar metastasis of choriocarcinoma.

Authors:  Yohei Naito; Koji Akeda; Yuichi Kasai; Akihiko Matsumine; Tsutomu Tabata; Kenji Nagao; Atsumasa Uchida
Journal:  Spine (Phila Pa 1976)       Date:  2009-07-01       Impact factor: 3.468

3.  Metastatic choriocarcinoma in the thoracic extradural space: case report.

Authors:  E Beşkonakli; S Cayli; S Kulaçoğlu
Journal:  Spinal Cord       Date:  1998-05       Impact factor: 2.772

4.  Efficacy and safety of ethanol injections in 18 cases of vertebral hemangioma: a mean follow-up of 2 years.

Authors:  T Bas; F Aparisi; J L Bas
Journal:  Spine (Phila Pa 1976)       Date:  2001-07-15       Impact factor: 3.468

5.  Mixed germinoma and choriocarcinoma in the intramedullary spinal cord: case report and review of the literature.

Authors:  Masaaki Takahashi; Hiroshi Koyama; Takamasa Matsubara; Hideyuki Murata; Katsutoshi Miura; Akira Nagano
Journal:  J Neurooncol       Date:  2006-01       Impact factor: 4.130

6.  Intracranial haemorrhage resulting from unsuspected choriocarcinoma metastasis.

Authors:  T N Suresh; V Santosh; V R Shastry Kolluri; P N Jayakumar; T C Yasha; A Mahadevan; S K Shankar
Journal:  Neurol India       Date:  2001-09       Impact factor: 2.117

7.  Symptomatic vertebral hemangiomas: treatment by means of direct intralesional injection of ethanol.

Authors:  J L Doppman; E H Oldfield; J D Heiss
Journal:  Radiology       Date:  2000-02       Impact factor: 11.105

8.  Intracranial vascular complications of choriocarcinoma.

Authors:  B Weir; N MacDonald; B Mielke
Journal:  Neurosurgery       Date:  1978 Mar-Apr       Impact factor: 4.654

Review 9.  Radiology of gestational trophoblastic neoplasia.

Authors:  S D Allen; A K Lim; M J Seckl; D M Blunt; A W Mitchell
Journal:  Clin Radiol       Date:  2006-04       Impact factor: 2.350

10.  Metastasis of choriocarcinoma to lumbar and sacral column.

Authors:  Renato Augusto Menegaz; Andréa Duarte Resende; Cléber Sérgio da Silva; Ana Cristina Macedo Barcelos; Eddie Fernando Candido Murta
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2004-03-15       Impact factor: 2.435

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  6 in total

1.  Renal cell carcinoma metastasis involving vertebral hemangioma: dual percutaneous treatment by navigational bipolar radiofrequency ablation and high viscosity cement vertebroplasty.

Authors:  Jean-Baptiste Zerlauth; Reto Meuli; Vincent Dunet
Journal:  BMJ Case Rep       Date:  2017-02-02

2.  Choriocarcinoma with multiple lung, skull and skin metastases in a postmenopausal female: A case report.

Authors:  Xiao-Man Li; Xiao-Yun Liu; Zhi-Xia Liu
Journal:  Oncol Lett       Date:  2015-09-25       Impact factor: 2.967

3.  Intramedullary spinal cord metastasis of choriocarcinoma.

Authors:  Jun Kyeung Ko; Seung Heon Cha; Jung Hwan Lee; Chang Hwa Choi
Journal:  J Korean Neurosurg Soc       Date:  2012-03-31

4.  Choriocarcinoma presenting as an isolated bone marrow metastasis-a case report.

Authors:  Sarika Singh; Manjula Sardhana; Suneeta Sharma; Prakash Chitralkar
Journal:  Ecancermedicalscience       Date:  2014-01-29

5.  Metastatic choriocarcinoma to the lumbar spine: Case report and review of literature.

Authors:  Jesse Skoch; Kelly Kobylanski; Jeffrey M Rice; Ali A Baaj
Journal:  Surg Neurol Int       Date:  2014-11-21

6.  Multidisciplinary treatment of life-threatening hemoptysis and paraplegia of choriocarcinoma with pulmonary, hepatic and spinal metastases: A case report.

Authors:  Yuan-Yuan Lin; Yang Sun; Yu Jiang; Bao-Zhi Song; Li-Juan Ke
Journal:  World J Clin Cases       Date:  2020-09-06       Impact factor: 1.337

  6 in total

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