Literature DB >> 20223954

Pharmacology. The puzzling rise and fall of a dark-horse Alzheimer's drug.

Greg Miller.   

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Year:  2010        PMID： 20223954     DOI： 10.1126/science.327.5971.1309

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


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  23 in total

1.  Screening: Your brain on drugs.

Authors:  Jonathan P Saxe
Journal:  Nat Chem Biol       Date:  2010-09       Impact factor: 15.040

2.  GDF-15 secreted from human umbilical cord blood mesenchymal stem cells delivered through the cerebrospinal fluid promotes hippocampal neurogenesis and synaptic activity in an Alzheimer's disease model.

Authors:  Dong Hyun Kim; Dahm Lee; Eun Hyuk Chang; Ji Hyun Kim; Jung Won Hwang; Ju-Yeon Kim; Jae Won Kyung; Sung Hyun Kim; Jeong Su Oh; Sang Mi Shim; Duk Lyul Na; Wonil Oh; Jong Wook Chang
Journal:  Stem Cells Dev       Date:  2015-08-19       Impact factor: 3.272

Review 3.  Alzheimer's disease and age-related memory decline (preclinical).

Authors:  Alvin V Terry; Patrick M Callahan; Brandon Hall; Scott J Webster
Journal:  Pharmacol Biochem Behav       Date:  2011-02-24       Impact factor: 3.533

4.  Dimebon inhibits calcium-induced swelling of rat brain mitochondria but does not alter calcium retention or cytochrome C release.

Authors:  Kranthi Kumari Naga; James W Geddes
Journal:  Neuromolecular Med       Date:  2010-07-13       Impact factor: 3.843

Review 5.  Multi-target design strategies in the context of Alzheimer's disease: acetylcholinesterase inhibition and NMDA receptor antagonism as the driving forces.

Authors:  Michela Rosini; Elena Simoni; Anna Minarini; Carlo Melchiorre
Journal:  Neurochem Res       Date:  2014-02-04       Impact factor: 3.996

6.  Umbilical cord blood mesenchymal stem cells protect amyloid-β42 neurotoxicity via paracrine.

Authors:  Ju-Yeon Kim; Dong Hyun Kim; Ji Hyun Kim; Yoon Sun Yang; Wonil Oh; Eun Hui Lee; Jong Wook Chang
Journal:  World J Stem Cells       Date:  2012-11-26       Impact factor: 5.326

Review 7.  Novel Sites of Neuroprotective Action of Dimebon (Latrepirdine).

Authors:  Aleksey Ustyugov; Elena Shevtsova; Sergey Bachurin
Journal:  Mol Neurobiol       Date:  2015-06-30       Impact factor: 5.590

Review 8.  Targeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunities.

Authors:  Charles C Caldwell; Jia Yao; Roberta Diaz Brinton
Journal:  Neurotherapeutics       Date:  2015-01       Impact factor: 7.620

Review 9.  Why so few drugs for Alzheimer's disease? Are methods failing drugs?

Authors:  R E Becker; N H Greig
Journal:  Curr Alzheimer Res       Date:  2010-11       Impact factor: 3.498

10.  Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.

Authors:  Prashant R Bharadwaj; Giuseppe Verdile; Renae K Barr; Veer Gupta; John W Steele; M Lenard Lachenmayer; Zhenyu Yue; Michelle E Ehrlich; Gregory Petsko; Shulin Ju; Dagmar Ringe; Sonia E Sankovich; Joanne M Caine; Ian G Macreadie; Sam Gandy; Ralph N Martins
Journal:  J Alzheimers Dis       Date:  2012       Impact factor: 4.472
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