OBJECTIVE: To assess the effect of fetal gender on pregnancy outcome. METHODS: Retrospective study of all singleton pregnancies at a tertiary hospital during 1995-2006. RESULTS: Of the 66,387 women studied, 34,367 (51.8%) delivered male and 32,020 (48.2%) delivered female neonates. The rate of preterm delivery (as early as 29 weeks) was higher for male fetuses and was attributed to an increased incidence of spontaneous preterm labor and preterm premature rupture of membranes. Women carrying male fetuses were at increased risk for operative vaginal delivery (OVD) for non-reassuring fetal heart rate, failed OVD and cesarean delivery. Female fetuses were more likely to experience fetal growth restriction (FGR). CONCLUSION: Fetal gender is independently associated with adverse pregnancy outcome. Although the added risk is relatively small, further investigation of the mechanisms underlying this association may contribute to our understanding of the pathophysiology of pregnancy complications such as preterm delivery and FGR.
OBJECTIVE: To assess the effect of fetal gender on pregnancy outcome. METHODS: Retrospective study of all singleton pregnancies at a tertiary hospital during 1995-2006. RESULTS: Of the 66,387 women studied, 34,367 (51.8%) delivered male and 32,020 (48.2%) delivered female neonates. The rate of preterm delivery (as early as 29 weeks) was higher for male fetuses and was attributed to an increased incidence of spontaneous preterm labor and preterm premature rupture of membranes. Women carrying male fetuses were at increased risk for operative vaginal delivery (OVD) for non-reassuring fetal heart rate, failed OVD and cesarean delivery. Female fetuses were more likely to experience fetal growth restriction (FGR). CONCLUSION: Fetal gender is independently associated with adverse pregnancy outcome. Although the added risk is relatively small, further investigation of the mechanisms underlying this association may contribute to our understanding of the pathophysiology of pregnancy complications such as preterm delivery and FGR.
Authors: Myrthe J C S Peelen; Brenda M Kazemier; Anita C J Ravelli; Christianne J M de Groot; Joris A M van der Post; Ben W J Mol; Marjolein Kok; Petra J Hajenius Journal: J Perinatol Date: 2021-03-09 Impact factor: 2.521
Authors: Amy E Braun; Kristin L Muench; Beatriz G Robinson; Angela Wang; Theo D Palmer; Virginia D Winn Journal: Reprod Sci Date: 2020-11-04 Impact factor: 3.060
Authors: Tianyanxin Sun; Tania L Gonzalez; Nan Deng; Rosemarie DiPentino; Ekaterina L Clark; Bora Lee; Jie Tang; Yizhou Wang; Barry R Stripp; Changfu Yao; Hsian-Rong Tseng; S Ananth Karumanchi; Alexander F Koeppel; Stephen D Turner; Charles R Farber; Stephen S Rich; Erica T Wang; John Williams; Margareta D Pisarska Journal: J Clin Endocrinol Metab Date: 2020-12-01 Impact factor: 5.958