Literature DB >> 20222817

Type 2 diabetes in children and adolescents.

Shazhan Amed1, Denis Daneman, Farid H Mahmud, Jill Hamilton.   

Abstract

The emergence of Type 2 diabetes (T2D) in children and adolescents parallels the rising rates of childhood obesity. As a condition of impaired insulin sensitivity and relative insulin deficiency resulting in hyperglycemia, T2D has a complex underlying physiology that is reflected by the multiple approaches used to optimize medical care and prevent the myriad of diabetes-related complications. T2D diagnosed in children and adolescents represents a distinct and challenging condition to evaluate and treat. Here, we highlight the epidemiology, pathophysiology, risk factors, clinical presentation and diagnosis, treatment and public health impact of T2D in children and adolescents.

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Year:  2010        PMID: 20222817     DOI: 10.1586/erc.10.15

Source DB:  PubMed          Journal:  Expert Rev Cardiovasc Ther        ISSN: 1477-9072


  10 in total

1.  Changes in eNOS phosphorylation contribute to increased arteriolar NO release during juvenile growth.

Authors:  Lori S Kang; Timothy R Nurkiewicz; Guoyao Wu; Matthew A Boegehold
Journal:  Am J Physiol Heart Circ Physiol       Date:  2011-12-02       Impact factor: 4.733

Review 2.  The future of treating youth-onset type 2 diabetes: focusing upstream and extending our influence into community environments.

Authors:  Shazhan Amed
Journal:  Curr Diab Rep       Date:  2015-03       Impact factor: 4.810

3.  Active commuting to elementary school and adiposity: an observational study.

Authors:  Jason A Mendoza; Yan Liu
Journal:  Child Obes       Date:  2014-01-20       Impact factor: 2.992

4.  Increased expression of adenylyl cyclase 3 in pancreatic islets and central nervous system of diabetic Goto-Kakizaki rats: a possible regulatory role in glucose homeostasis.

Authors:  Mohammed Seed Ahmed; Abraham Kovoor; Sofia Nordman; Norhashimah Abu Seman; Tianwei Gu; Suad Efendic; Kerstin Brismar; Claes-Göran Östenson; Harvest F Gu
Journal:  Islets       Date:  2012-09-01       Impact factor: 2.694

5.  Expression of Protein Kinase C Isoforms in Pancreatic Islets and Liver of Male Goto-Kakizaki Rats, a Model of Type 2 Diabetes.

Authors:  Mohammed Seed Ahmed; Mohammed Seed Ahmed; Julien Pelletier; Hannes Leumann; Harvest F Gu; Claes-Göran Östenson
Journal:  PLoS One       Date:  2015-09-23       Impact factor: 3.240

6.  National surveillance for type 1, type 2 diabetes and prediabetes among children and adolescents: a population-based study (SAUDI-DM).

Authors:  Khalid Al-Rubeaan
Journal:  J Epidemiol Community Health       Date:  2015-06-17       Impact factor: 3.710

7.  The effects of GLP-1 analogues on pre-diabetes of the children.

Authors:  Qing-Xia Zhou; Zi-Yu Wang; Hua-Feng Zhao; Shan Wang
Journal:  Exp Ther Med       Date:  2017-02-16       Impact factor: 2.447

8.  Metabolomics analysis reveals altered metabolites in lean compared with obese adolescents and additional metabolic shifts associated with hyperinsulinaemia and insulin resistance in obese adolescents: a cross-sectional study.

Authors:  Elisabeth Müllner; Hanna E Röhnisch; Claudia von Brömssen; Ali A Moazzami
Journal:  Metabolomics       Date:  2021-01-12       Impact factor: 4.290

9.  Timing of rapid weight gain and its effect on subsequent overweight or obesity in childhood: findings from a longitudinal birth cohort study.

Authors:  Yi-Fan Li; Shio-Jean Lin; Tung-Liang Chiang
Journal:  BMC Pediatr       Date:  2020-06-12       Impact factor: 2.125

10.  Epidemiology, genetic landscape and classification of childhood diabetes mellitus in the State of Qatar.

Authors:  Basma Haris; Saras Saraswathi; Sara Al-Khawaga; Reem Hasnah; Amira Saeed; Shihab Mundekkadan; Noor Hamed; Houda Afyouni; Tasneem Abdel-Karim; Shayma Mohammed; Amel Khalifa; Maryam Al-Maadheed; Mahmoud Al-Zyoud; Ahmed Shamekh; Ahmed Elawwa; Fawziya Al-Khalaf; Sabri Boughorbel; Goran Petrovski; Khalid Hussain
Journal:  J Diabetes Investig       Date:  2021-07-04       Impact factor: 4.232

  10 in total

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