| Literature DB >> 20222742 |
Cheng-Hui Chen1, Yu-Kai Chen, Chin-Kang Sha.
Abstract
Enantioselective total synthesis of otteliones A and B was accomplished. The key steps are radical cyclization of an alpha-iodoketone to construct the cis-hydrindanone skeleton and Suzuki-Miyaura coupling to incorporate the aromatic group. (+)-Ottelione A was converted to (-)-ottelione B on treatment with NaOH in THF.Entities:
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Year: 2010 PMID： 20222742 DOI： 10.1021/ol902776d
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005