Lang Zhao1, Zhiqiang Ou, Kan Wang, Hongzheng Fu. 1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Abstract
OBJECTIVE: To study the steroidal alkaloids in Veratrum dahuricum. METHOD: The compounds were isolated and purified by various column chromatographic methods. Their structures were identified by spectroscopic analysis. RESULT: Five compounds were isolated and identified as (20R, 22S, 25S)-veratra-5,13-dien-3beta-ol (1), angeloylzygadenine (2), 15-O-(2-methylbutanoyl)-3-O-veatroylprotoverine (3), 20-isoveratramine (4), veratramine (5). CONCLUSION: Compound 1 was a new compound, compounds 24 were obtained from the plant for the first time.
OBJECTIVE: To study the steroidal alkaloids in Veratrum dahuricum. METHOD: The compounds were isolated and purified by various column chromatographic methods. Their structures were identified by spectroscopic analysis. RESULT: Five compounds were isolated and identified as (20R, 22S, 25S)-veratra-5,13-dien-3beta-ol (1), angeloylzygadenine (2), 15-O-(2-methylbutanoyl)-3-O-veatroylprotoverine (3), 20-isoveratramine (4), veratramine (5). CONCLUSION: Compound 1 was a new compound, compounds 24 were obtained from the plant for the first time.